Amendment to General Services Agreement between Nycomed Amersham plc and Amersham Pharmacia Biotech Limited (February 19, 2001)

Summary

This amendment updates the General Services Agreement between Nycomed Amersham plc and Amersham Pharmacia Biotech Limited. The change allows Nycomed Amersham to terminate the agreement with three months' notice if it no longer has the right to nominate the majority of APBiotech's Board of Directors, instead of the previous condition based on holding at least 50% of voting rights. Both parties have agreed to this amendment by signing the letter.

EX-10.13 5 y42738a1ex10-13.txt AMENDMENT TO GENERAL SERVICES AGREEMENT 1 EXHIBIT 10.13 [Letterhead NYCOMED AMERSHAM] 19th February, 2001 Nycomed Amersham plc Company Secretary Amersham Place Amersham Pharmacia Biotech Limited Little Chalfont Amersham Place Buckinghamshire Little Chalfont HP7 9NA England Bucks HP7 9NA T +44 (0) 1494 544000 F +44 (0) 1494 542266 Attention: J.A. Cooper Dear Sir, GENERAL SERVICES AGREEMENT -- 4TH AUGUST, 1997 (THE "AGREEMENT") -- PROPOSED AMENDMENT As you are aware, we are in the process of making a public offering of approximately 10% of the common stock which we currently hold in Amersham Pharmacia Biotech Limited (or any successor company following a reorganisation of the common stock) ("APBiotech"). With reference to Clause 8.7 of the Agreement, it has been agreed that in future the circumstances in which Nycomed Amersham plc shall be entitled to terminate the Agreement on three months' notice shall be when Nycomed Amersham ceases to have the right to nominate the majority of the Board of Directors of APBiotech, rather than on ceasing to have a direct or indirect interest in at least 50% of the voting rights attaching to the stock of APBiotech. Clause 8.7 shall therefore be amended as follows: "8.7 International may terminate this Agreement on three months' notice ending on or after the date on which International ceases to have the right to nominate the majority of the Board of Directors of Biotech." Please acknowledge agreement by countersigning this letter and returning it to me. Yours sincerely, /s/ G.F.B. Kerr - ------------------ G.F.B. Kerr Finance Director Agreed: /s/ J.A. Cooper -------------------------------------- J.A. Cooper For Amersham Pharmacia Biotech Limited