Altus Pharmaceuticals Inc. Contracts & Agreements

HOBBS BROOK OFFICE PARK 333 Wyman Street, Waltham, Massachusetts FIRST AMENDMENT TO LEASE Altus Pharmaceuticals, Inc. (Filed With SEC on July 6, 2009)

HOBBS BROOK OFFICE PARK 610 Lincoln Street North, Waltham, Massachusetts FIRST AMENDMENT TO LEASE Altus Pharmaceuticals, Inc. (Filed With SEC on July 6, 2009)

Ex-10.1 Letter Agreement between the Registrant and Thomas J. Phair, Jr. dated January 22, 2009 (Filed With SEC on May 11, 2009)

Ex-10.2 Letter Agreement dated February 20, 2009 between the Registrant and Cystic Fibrosis Foundation Therapeutics, Inc (Filed With SEC on May 11, 2009)

Ex-10.3 License Agreement dated February 20, 2009 by and between the Registrant and Cystic Fibrosis Foundation Therapeutics, Inc (Filed With SEC on May 11, 2009)

Ex-10.4 Amendment to Termination Agreement dated May 7, 2009 between the Registrant and Dr. Falk Pharma GmbH (Filed With SEC on May 11, 2009)

SEVERANCE AND CHANGE IN CONTROL AGREEMENT (Filed With SEC on May 5, 2009)

ALTUS PHARMACEUTICALS INC. EXECUTIVE SEVERANCE POLICY (Filed With SEC on May 5, 2009)

EXECUTIVE SEVERANCE SECURITY AGREEMENT (Filed With SEC on May 5, 2009)

EX-10.40 Third Amendment to Drug Product Production and Clinical Supply Agreement (Filed With SEC on March 11, 2009)

EX-10.1 Admendment 1 to Manufacturing and Supply Agreement (Filed With SEC on November 4, 2008)

EX-10.2 Admendment 2 to Manufacturing and Supply Agreement (Filed With SEC on November 4, 2008)

Ex-10.1 Supply Agreement between Sandoz GmbH and Altus Pharmaceuticals Inc. dated as of July 1, 2008 (Filed With SEC on August 5, 2008)

Altus Pharmaceuticals, Inc. (Filed With SEC on May 27, 2008)

SEVERANCE AND CHANGE IN CONTROL AGREEMENT (Filed With SEC on May 27, 2008)

EX-10.1 Second Amendment, effective March 12, 2008, to Drug Product Production and Clinical Supply Agreement between Althea Technologies, Inc. and Altus Pharmaceuticals Inc.,... (Filed With SEC on May 7, 2008)

EX-10.8 Post-IPO Non-Qualified Stock Option Agreement (Filed With SEC on March 11, 2008)

EX-10.17 Letter Agreement between the Registrant & Philip Gotwals (Filed With SEC on March 11, 2008)

EX-10.18 Employment Agreement between the Registrant & David Pendergast (Filed With SEC on March 11, 2008)

EX-10.21 Separation Agreement between Registrant & Sheldon Berkle (Filed With SEC on March 11, 2008)

EX-10.46 Termination & Transition Amendment (Genetech, Inc.) (Filed With SEC on March 11, 2008)

EX-10.50 Manufacturing License Agreement (Amano Enzyme, Inc.) (Filed With SEC on March 11, 2008)

EX-10.1 Cooperative Development Agreement (Filed With SEC on November 7, 2007)

EX-10.2 Amendment No. 3 to Cooperative Development Agreement (Filed With SEC on November 7, 2007)

CONSULTING AGREEMENT (Filed With SEC on October 29, 2007)

Ex-10.1 First Amendment to Drug Product Production and Clinical Supply Agreement (Filed With SEC on August 8, 2007)

Ex-10.2 Termination Agreement to the Development, Commercialization and Marketing Agreement (Filed With SEC on August 8, 2007)

Ex-10.3 Consent to Sublease (MIT) (Filed With SEC on August 8, 2007)

SEVERANCE AND CHANGE IN CONTROL AGREEMENT (Filed With SEC on May 21, 2007)

EX-10.1 AMENDMENT NO. 2 TO COOPERATIVE DEVELOPMENT AGREEMENT (Filed With SEC on May 11, 2007)

Ex-1.1 Purchase Agreement dated April 18, 2007 (Filed With SEC on April 19, 2007)

SUBLEASE (Filed With SEC on April 5, 2007)

EX-10.4 2002 Employee, Director and Consultant Stock Plan (Filed With SEC on March 12, 2007)

EX-10.9 Director Compensation Policy dated February 2, 2007 (Filed With SEC on March 12, 2007)

EX-10.13 Agreement between Lauren Sabella, dated April 4, 2006 (Filed With SEC on March 12, 2007)

EX-10.14 Agreement between Burkhard Blank, dated June 2, 2006 (Filed With SEC on March 12, 2007)

EX-10.15 Agreement between John Sorvillo, dated July 31, 2006 (Filed With SEC on March 12, 2007)

EX-10.16 Agreement between Renato Fuchs, dated August 14, 2006 (Filed With SEC on March 12, 2007)

EX-10.17 Agreement between Bruce Leicher, dated October 31, 2006 (Filed With SEC on March 12, 2007)

EXHIBIT 10.1 COMMON STOCK PURCHASE AGREEMENT (Filed With SEC on March 1, 2007)

EXHIBIT 10.2 REGISTRATION RIGHTS AGREEMENT (Filed With SEC on March 1, 2007)

EX-10.1 Manufacturing and Supply Agreement dated November 15, 2006 (Filed With SEC on February 6, 2007)

EX-10.1 Collaboration and License Agreement dated December 19, 2006 (Filed With SEC on February 1, 2007)

PROMISSORY NOTE To Master Security Agreement No. 4081067 December 29, 2006 (Date) (Filed With SEC on January 3, 2007)

EX-10.1 - Drug Product Production & Clinical Supply Agreement (Filed With SEC on November 14, 2006)

EX-1.1 FORM OF PURCHASE AGREEMENT (Filed With SEC on January 11, 2006)

EX-4.1 FORM OF COMMON STOCK CERTIFICATE (Filed With SEC on January 11, 2006)

EX-10.4 AMENDED AND RESTATED 2002 EMPLOYEE, DIRECTOR, AND CONSULTANT STOCK PLAN (Filed With SEC on January 11, 2006)

EX-10.5.1 POST-IPO FORM OF INCENTIVE STOCK OPTION AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.6.1 POST-IPO FORM OF NON-QUALIFIED STOCK OPTION AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.13 TECHNOLOGY LICENSE AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.14 COOPERATIVE DEVELOPMENT AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.15 STRATEGIC ALLIANCE AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.16 DEVELOPMENT, COMMERCIALIZATION AND MARKETING AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.26 PURCHASE AGREEMENT (Filed With SEC on January 11, 2006)

EX-10.27 SUMMARY OF EXECUTIVE COMPENSATION (Filed With SEC on January 11, 2006)

EX-10.28 DIRECTOR COMPENSATION POLICY (Filed With SEC on January 11, 2006)

Ex-10.13 Technology License Agreement, dated February 1, 1999, as amended (Filed With SEC on December 27, 2005)

Ex-10.14 Cooperative Development Agreement, dated November 8, 2002, as amended (Filed With SEC on December 27, 2005)

Ex-10.15 Strategic Alliance Agreement, dated February 22, 2001, as amended (Filed With SEC on December 27, 2005)

Ex-10.16 Development Commercialization and Marketing Agreement (Filed With SEC on December 27, 2005)

Ex-10.17 Letter Agreement, dated November 24, 2004 (Filed With SEC on December 27, 2005)

Ex-10.26 Purchase Agreement, dated October 10, 2005 (Filed With SEC on December 27, 2005)

EX-4.2 Amended and Restated Stockholders' Voting Agreement (Filed With SEC on November 30, 2005)

EX-10.7 Form of Indemnification Agreement (Filed With SEC on November 30, 2005)

EX-10.18 Separation Agreement - Peter L. Lanciano (Filed With SEC on November 30, 2005)

EX-4.2 Amended and Restated Stockholder Voting Agreement (Filed With SEC on October 17, 2005)

EX-4.3 Amended and Restated Investor Rights Agreement (Filed With SEC on October 17, 2005)

EX-4.4 Amended and Restated Rights of First Refusal (Filed With SEC on October 17, 2005)

EX-4.5 Amended and Restated Voting Standstill Agreement (Filed With SEC on October 17, 2005)

EX-4.6 Form of Common Stock Warrant to Vertex Pharmaceuticals (Filed With SEC on October 17, 2005)

EX-4.7 Form of Common Stock Warrant to General Electric Capital Corp (Filed With SEC on October 17, 2005)

EX-4.8 Form of Common Stock Warrant to Oxford Finance Corp (Filed With SEC on October 17, 2005)

EX-4.9 Form of Common Stock Warrant to Cystic Fibrosis Foundation (Filed With SEC on October 17, 2005)

EX-4.10 Form of Common Stock Warrant to Transamerica Business Credit Corp (Filed With SEC on October 17, 2005)

EX-4.11 Form of Common Stock Warrant to SG Cowen & Company (Filed With SEC on October 17, 2005)

EX-4.12 Form of Series B Preferred Stock Warrant (Filed With SEC on October 17, 2005)

EX-4.13 Form of Series C Preferred Stock Warrant (Filed With SEC on October 17, 2005)

EX-10.1 1993 Stock Option Plan (Filed With SEC on October 17, 2005)

EX-10.2 Form of Incentive Stock Option Plan (Filed With SEC on October 17, 2005)

EX-10.3 Form of Non-Qualified Stock Option Agreement (Filed With SEC on October 17, 2005)

EX-10.5 Form of Incentive Stock Option Agreement (Filed With SEC on October 17, 2005)

EX-10.6 Form of Non-Qualified Stock Option Agreement (Filed With SEC on October 17, 2005)

EX-10.8 Master Lease Agreement - General Electric Capital Corp (Filed With SEC on October 17, 2005)

EX-10.9 Master Loan Agreement Oxford Finance (Filed With SEC on October 17, 2005)

EX-10.10 Form of Promissory Note Oxford Finance (Filed With SEC on October 17, 2005)

EX-10.11 Master Security Agreement Oxford Finance (Filed With SEC on October 17, 2005)

EX-10.12 Form of Promissory Note Oxford Finance (Filed With SEC on October 17, 2005)

EX-10.18 Separation Agreement - Peter Lanciano (Filed With SEC on October 17, 2005)

EX-10.19 Consulting Agreement - Manuel A. Navia (Filed With SEC on October 17, 2005)

EX-10.20 Description of Arrangement - John P. Richard (Filed With SEC on October 17, 2005)

EX-10.21 Lease Agreement Rizika Realty Trust (Filed With SEC on October 17, 2005)

EX-10.22 Lease Agreement Fort Washington Realty (Filed With SEC on October 17, 2005)

EX-10.23 Description of Executive Officer Retention Arrangement (Filed With SEC on October 17, 2005)

EX-10.24 Sublease Agreement Vertex Pharmaceuticals (Filed With SEC on October 17, 2005)

EX-10.25 Sublease Agreement Transkaryotic Pharmaceuticals (Filed With SEC on October 17, 2005)

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Altus Pharmaceuticals Inc. Contracts & Agreements