EX-10.3 SECOND AMENDMENT, EFFECTIVE APRIL 1, 2007, TO LICENSE AGREEMENT

EX-10.3 4 b65152blexv10w3.txt EX-10.3 SECOND AMENDMENT, EFFECTIVE APRIL 1, 2007, TO LICENSE AGREEMENT EXHIBIT 10.3 AMENDMENT TO LICENSE AGREEMENT BETWEEN ORGANIX, INC. AND BOSTON LIFE SCIENCES, INC., EFFECTIVE AS OF JULY 1, 2000 RE: HARVARD CASE NO: 1382 (THE "LICENSE") Article 1.12, the definition of "PATENT RIGHTS," shall be amended to read as follows: U.S. Patent No. 5,948,933 filed July 11, 1997 entitled "Tropane Analogs and Methods for Inhibition of Monoamine Transport," the U.S. Patent Application Serial No. 60/327,963 filed October 9, 2001 entitled "Tropane Analogs and Methods for Inhibition of Monoamine Transport," the U.S. Patent Application Serial No. 10/033,621 filed December 27, 2001 entitled "Tropane Analogs and Methods for Inhibition of Monoamine Transport," the U.S. Patent Application Serial No. 60/368,382 filed March 28, 2002 entitled "Tropane Compounds," the U.S. Patent Application Serial No. 60/375,505 filed April 25, 2002 entitled "Tropane Compounds," the U.S. Patent Application Serial No. 10/400,825 filed March 27, 2003 entitled "Tropane Compounds," and any foreign (Non-U.S.) counterparts including continuations, divisions or extensions and all patents which issue therefrom in any country. It also includes continuations-in-part of the above-listed applications for which Drs. Paul Blundell, Zhengming Chen, Bertha Madras, and/or Peter Meltzer, are legally listed among the inventive entity and any foreign (Non-U.S.) counterparts including continuations, divisions or extensions and all patents which issue therefrom in any country. All other terms and conditions of the License shall remain unchanged. This amendment shall become effective on April 1, 2007. BOSTON LIFE SCIENCES, INC. ORGANIX, INC. /s/ Kenneth L. Rice /s/ Peter Meltzer - ------------------------------------- ---------------------------------------- Name: Kenneth L. Rice, Jr. Name: Peter Meltzer Position: EVP & CFO Position: President Date: 3/23/07 Date: 4/4/07