Office Lease by and between Rubicon, L.C. and Alimera Sciences, Inc., dated as of May 27, 2003, as amended on various dates through August 14, 2014

THIS FIRST AMENDMENT TO LEASE AGREEMENT (“Agreement”) dated as of the day of July 16, 2004, by and between THE MANUFACTURERS LIFE INSURANCE COMPANY (U.S.A.), a Michigan corporation (“Landlord”); and ALIMERA SCIENCES, INC. a Delaware corporation (“Tenant”).

WHEREAS, Rubicon, L.C., predecessor-in-interest to Landlord (“Rubicon”) and Tenant entered into that certain Office Lease for 6120 Windward Parkway dated May 27, 2003 (the “Initial Lease”) for certain premises known as Suite 290, containing approximately 5,079 rentable square feet of space (the “Premises”) in the building located at 6120 Windward Parkway, Fulton County, Georgia (the “Building”).

WHEREAS, Landlord and Tenant desire to enter into this Agreement for the purpose of evidencing their mutual understanding and agreement regarding the extension of the lease term and expansion of the Premises and certain other matters relating thereto as set forth hereinbelow.

NOW, THEREFORE, for and in consideration of the premises hereto, the keeping and performance of the covenants and agreements hereinafter contained, and for Ten and No/100 Dollars ($10.00) and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant, intending to be legally bound, agree as follows:

1.Defined Terms. All terms used herein and denoted by their initial capitalization shall have the meanings set forth in the Lease unless set forth herein to the contrary.

2.Extension of the Lease Term. The Lease Term is hereby extended for a period of twenty-six (26) months (the “Expansion Term”). The Expiration Date, as defined in the Initial Lease, shall now mean August 30, 2008.

3.Expansion of the Premises. Commencing September 1, 2004, the Premises shall be expanded by 4,711 rentable square feet (the “Expansion Premises”) for a revised total of 9,790 rentable square feet (the “Premises”) as more particularly described in Exhibit “A” attached hereto and incorporated herein.

4.Base-Rent. The Base Rent for the Extension Term shall be as follows:

5.Tenant Improvement Allowance. Landlord will renovate the Premises (“Leasehold Improvements”) in accordance with those Pricing Plans and Specifications prepared by Veenendaal Cave, Inc. (the “Plans and Specifications”) dated May 28, 2004 prior to September 1, 2004.

6.Brokerage Commissions. Tenant warrants and represents to Landlord that it has had no dealings with any real estate broker, agent or finder in connection with negotiation of this Agreement, excepting only Lavista Associates, Inc. (the “Tenant’s Broker” and “Landlord’s Broker”). Landlord and Tenant consent to said dual agency. Tenant covenants and agrees to defend, indemnify and hold the Landlord harmless from and against any and all loss, liability, damage, claim, judgment, cost or expense (including, but not limited to, attorneys’ fees and expenses and court costs) that may be incurred or suffered by the other because of any claim for any fee, commission or similar compensation with respect to this Agreement made by any broker, agent or finder claiming to have dealt with the Tenant. Landlord agrees to pay the commission due the Tenant’s Broker and Landlord’s Broker in connection with this Agreement pursuant to separate written commission agreements.

7.    Option to Renew. Tenant shall have the option (the “Option”) to extend the Term of this Lease for one additional period of three (3) years (the “Option Period”) during which all of the non-economic terms and conditions

of this Lease shall control and apply, except that the Base Rent and Tenant Improvement Allowance due under the Lease shall be the then market rental rate. The Option Period shall commence immediately upon the termination of the Term. Tenant shall not have the right to exercise the Option if at the time of exercise Tenant is in default under any of the terms or conditions of this Lease. Tenant may exercise the Option by giving Landlord written notice (in the manner provided for notice in this Lease) at least one hundred eighty (180) but no more than two hundred forty (240) days prior to the expiration date of the initial Term. Failure to give such notice shall terminate Tenant’s Option hereunder. If Tenant does timely exercise the Option, Tenant may not thereafter revoke said exercise.

Within thirty (30) days of Landlord’s receipt of Tenant’s notice exercising the Option, Landlord shall give notice to Tenant of the Base Rent that shall be due and payable during the Option Period. Tenant shall have thirty (30) days after receipt of Landlord’s notice within which to notify Landlord in writing that Tenant agrees to pay, during the Option Period. the Base Rent determined by Landlord hereunder. If Tenant fails to so notify Landlord of its agreement. the Option shall automatically terminate.

Tenant shall have no other right to extend or renew the Term of the Lease beyond the Option Period.

Time shall be of the essence with respect to the exercise of the Option.

8.Letter of Credit. Tenant shall deliver to Landlord, with the execution and delivery of The First Amendment to Lease, an irrevocable, unconditional letter of credit in favor of Landlord in the amount of $50,000.00 in a form acceptable to Landlord, in Landlord’s sole judgment, and issued by a bank in the Atlanta, Georgia metropolitan area. If Tenant defaults or otherwise fails to comply with the terms of the Lease for any reason, Landlord may immediately draw upon and receive payment under said letter of credit, and partial draws shall be permitted under the terms of said letter of credit, it being the express intent of Landlord and Tenant that the letter of credit be used either to cure existing defaults on the part of Tenant under the Lease, and/or as a security deposit, securing the full and complete performance by Tenant of Tenant obligations under the Lease. Such letter of credit shall permit transfers of the payee thereunder if Landlord transfers its interest in the Building. The letter of credit shall be open and may be drawn upon for a period which expires two (2) months after the scheduled expiration of the Term; provided however, that such letter of credit may be of a duration shorter than said period, so long as the letter of credit has an “evergreen” provision for the benefit of Landlord, and Tenant replaces said letter of credit with a new letter of credit, on the same terms and conditions, and in the same amount, as the prior letter of credit, at least one (1) month prior to the expiration of the prior letter of credit; and further provided, if Tenant is then in full compliance with the Lease and Landlord has not previously drawn upon such letter of credit as of December 31, 2005. Tenant may replace said letter of credit with a new letter of credit, on the same terms and conditions or the prior letter of credit, in the amount of $21,471.74. If Tenant fails to replace a prior letter of credit within the period required herein, then Landlord shall be immediately authorized and entitled to demand and receive payment under said letter of credit, and to apply and hold the proceeds therefrom as a security deposit under the terms and conditions of Paragraph 22 of this Lease.

9.Binding Effect. This Agreement shall he governed by and construed in accordance with the laws of the State of Georgia and shall be binding upon and inure to the benefit of the parties hereto and their respective heirs, successors, representatives and assigns, but always subject, in the case of Tenant, to the limitations on assignment and sublease set forth in the Lease. In the event of any inconsistency or conflict between the terms of this Agreement and of the Lease, the terms hereof shall control. Time is of the essence of all of the terms of this Agreement.

10.Continued Validity. Except as hereinabove provided, all other terms and conditions of the Lease shall remain unchanged and in full force and effect and are hereby ratified and confirmed by Landlord and Tenant. Tenant hereby acknowledges and agrees that, to the best of its knowledge, as of the date hereof, the Lease is subject to no offsets, claims, counterclaims or defenses of any nature whatsoever and any improvements to the Premises required to be constructed and/or financed by Landlord have been completed to Tenant’s satisfaction.

11.Modifications. This Agreement may not be changed, modified, discharged or terminated orally in any manner other than by an agreement in writing signed by Landlord and Tenant or their respective heirs, representatives, successors and permitted assigns.

12.Authority. Tenant does hereby personally represent and warrant that Tenant is a validly existing corporation and is fully authorized and qualified to do business in the State of Georgia, that the corporation has full right and authority to enter into this Agreement, and that the undersigned, who is signing on behalf of the corporation is a duly authorized officer of the corporation and is authorized to sign on behalf of the corporation.

IN WITNESS WHEREOF, the parties have set their hands and affixed their seals to this Agreement to be effective as of the day and year first above written.

THE MANUFACTURERS LIFE INSURANCE COMPANY

(U.S.A.), a Michigan corporation

ALIMERA SCIENCES, INC., a Delaware corporation

THIS SECOND AMENDMENT TO LEASE AGREEMENT (“Agreement”) dated as of the 1^st day of July 2005, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, having a local regional office at 1170 Peachtree Street, Suite 565, in the city of Atlanta, Georgia 30309 (“Landlord”); and ALIMERA SCIENCES, INC. a Delaware corporation (“Tenant”).

WHEREAS, Rubicon, L.C., predecessor-in-interest to Landlord (“Rubicon”) and Tenant entered into that certain Office Lease for 6120 Windward Parkway dated May 27, 2003 (the “Initial Lease”) and amended by that certain First Amendment to Lease for 6120 Windward Parkway dated July 16, 2004 (the “First Amendment) for certain premises known as Suite 290, containing approximately 9,790 rentable square feet of space (the “Premises”) in the building located at 6120 Windward Parkway, Fulton County, Georgia (the “Building”).

WHEREAS, Landlord and Tenant desire to enter into this Agreement for the purpose of evidencing their mutual understanding and agreement regarding the extension of the lease term and expansion of the Premises and certain other matters relating thereto as set forth hereinbelow.

NOW, THEREFORE, for and in consideration of the premises hereto, the keeping and performance of the covenants and agreements hereinafter contained, and for Ten and No/100 Dollars ($10.00) and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant, intending to be legally bound, agree as follows:

1.Defined Terms. All terms used herein and denoted by their initial capitalization shall have the meanings set forth in the Lease unless set forth herein to the contrary.

2.Extension of the Lease Term. The Lease Term is hereby extended for a period of twelve (12) months (the “Expansion Term”). The Expiration Date, as defined in the Initial Lease, shall now mean August 30, 2009.

3.Expansion of the Premises. Commencing September 1, 2005, the Premises shall be expanded by 4,423 rentable square feet (the “Expansion Premises”) for a revised total of 14,213 rentable square feet (the “Premises”) as more particularly described in Exhibit “A” attached hereto and incorporated herein.

4.Base Rent. The Base Rent for the Extension Term shall be as follows:

5.Taxes and Operating Expenses. Notwithstanding anything in Article 1 (b) of the Initial Lease and that Letter Agreement dated March 1, 2005 by and between Landlord and Tenant to the contrary, effective January 1, 2006 Tenant’s ProRata Share of increases in “controllable” Operating Expenses (as that term is hereinafter defined) for any calendar year during the Lease Term shall not include a portion of such “controllable” Operating Expenses for such year to the extend the amount of such “controllable” Operating Expenses exceeds the product of (i) comparable “controllable” Operating Expenses incurred by Landlord in the Base Year multiplied by (ii) 105% per annum compounded annually from the Base Year. For the purposes of this subparagraph, “non-controllable” Operating Expenses are defined to be all Operating Expenses other than those expenses the increase in which is beyond the reasonable control of Landlord. By way of illustration and not limitation, examples of increases in Operating Expenses that are beyond the reasonable control of Landlord include all increases in minimum wages and benefits that affect wages and benefit paid to employees and contractor employees), taxes and assessment, including, without limitation, Property Taxes, insurance and utilities.

6.Tenant Improvement Allowance. Landlord will renovate the Premises (“Leasehold Improvements”) in accordance with those Pricing Plans and Specifications prepared by Veenendaal Cave, Inc. (the “Plans and Specifications”) dated May 23, 2005 prior to September 1, 2005.

7.First Right of Refusal. Landlord shall not lease all or any part of the area of the building designated as Suite 220 and marked “First Right of Refusal Space” on Exhibit “B” of approximately 5,232 rentable square feet to any other party without first offering said space to Tenant.

Landlord shall provide written notice to Tenant of Landlord’s desire to rent said Expansion Space to another party and Tenant shall have three (3) days after such notice to indicate in writing its agreement to lease the Expansion Space at mutually acceptable economic terms and conditions as determined by Landlord and Tenant.

If Tenant does not indicate its willingness to lease the Expansion Space in writing within three (3) days thereafter and execute a lease or lease amendment in form similar to this lease or lease amendment within four (4) days thereafter, Landlord thereafter shall have the right to lease all or part of the Expansion Space to any party and Tenant shall have no right with regard to the Expansion Space.

Tenant shall have no rights under this paragraph whatsoever should Tenant be in default under the terms of this lease.

8.Brokerage Commissions. Tenant warrants and represents to Landlord that it has had no dealings with any real estate broker, agent or finder in connection with negotiation of this Agreement, excepting only Lavista Associates, Inc. (“Landlord’s Broker”) and Kilburn Commercial Properties, LLC (“Tenant’s Broker”). Tenant covenants and agrees to defend, indemnify and hold the Landlord harmless from and against any and all loss, liability, damage, claim, judgment, cost or expense (including, but not limited to, attorneys’ fees and expenses and court costs) that may be incurred or suffered by the other because of any claim for any fee, commission or similar compensation with respect to this Agreement made by any broker, agent or finder claiming to have dealt with the Tenant. Landlord agrees to pay the commission due the Tenant’s Broker and Landlord’s Broker in connection with this Agreement pursuant to separate written commission agreements.

9.Letter of Credit. Tenant has delivered to Landlord, with the execution and delivery of The First Amendment to Lease, an irrevocable, unconditional letter of credit in favor of Landlord in the amount of $50,000.00 in a form acceptable to Landlord, in Landlord’s sole judgment, and issued by a bank in the Atlanta, Georgia metropolitan area. If Tenant defaults or otherwise fails to comply with the terms of the Lease for any reason, Landlord may immediately draw upon and receive payment under said letter of credit, and partial draws shall be permitted under the terms of said letter of credit, it being the express intent of Landlord and Tenant that the letter of credit be used either to cure existing defaults on the part of Tenant under the Lease, and/or as a security deposit, securing the full and complete performance by Tenant of Tenant obligations under the Lease. Such letter of credit shall permit transfers of the payee thereunder if Landlord transfers its interest in the Building. The letter of credit shall be open and may be drawn upon for a period which expires two (2) months after the scheduled expiration of the Term; provided however, that such letter of credit may be of a duration shorter than said period, so long as the letter of credit has an “evergreen” provision for the benefit of Landlord, and Tenant replaces said letter of credit with a new letter of credit, on the same terms and conditions, and in the same amount, as the prior letter of credit, at least one (1) month prior to the expiration of the prior letter of credit; and further provided, if Tenant is then in full compliance with the Lease and Landlord has not previously drawn upon such letter of credit as of December 31, 2005, Tenantmay replace said letter of credit with a cash Security Deposit delivered to Landlord on or before December 31, 2005 in the amount of nineteen thousand nine hundred ninety-two and 95/100 Dollars ($19,992.95). Said Security Deposit shall be governed under the terms and conditions outlined in Article 22 of the Initial Lease. If Tenant fails to replace a prior letter of credit with the cash Security Deposit outlined above within the period required herein, then Landlord shall be immediately authorized and entitled to demand and receive payment under said letter of credit, and to apply and hold the proceeds therefrom as a security deposit under the terms and conditions of Paragraph 22 of this Lease.

10.    Monument Sign. Tenant shall have the right at Tenant’s expense to add its identification on the Project Monument on Windward Parkway to Landlord and Tenant’s mutually acceptable specifications. This right is granted so long as the size of its Premises is not reduced, and Tenant is not in default of this Lease.

11.Binding Effect. This Agreement shall be governed by and construed in accordance with the laws of the State of Georgia and shall be binding upon and inure to the benefit of the parties hereto and their respective heirs, successors, representatives and assigns, but always subject, in the case of Tenant, to the limitations on assignment and sublease set forth in the Lease. In the event of any inconsistency or conflict between the terms of this Agreement and of the Lease, the terms hereof shall control. Time is of the essence of all of the terms of this Agreement.

12.Continued Validity. Except as hereinabove provided, all other terms and conditions of the Lease shall remain unchanged and in full force and effect and are hereby ratified and confirmed by Landlord and Tenant. Tenant hereby acknowledges and agrees that, to the best of its knowledge, as of the date hereof, the Lease is subject to no offsets, claims, counterclaims or defenses of any nature whatsoever and any improvements to the Premises required to be constructed and/or financed by Landlord have been completed to Tenant=s satisfaction.

13.Modifications. This Agreement may not be changed, modified, discharged or terminated orally in any manner other than by an agreement in writing signed by Landlord and Tenant or their respective heirs, representatives, successors and permitted assigns.

14.Authority. Tenant does hereby personally represent and warrant that Tenant is a validly existing corporation and is fully authorized and qualified to do business in the State of Georgia, that the corporation has full right and authority to enter into this Agreement, and that the undersigned, who is signing on behalf of the corporation is a duly authorized officer of the corporation and is authorized to sign on behalf of the corporation.

IN WITNESS WHEREOF, the parties have set their hands and affixed their seals to this Agreement to be effective as of the day and year first above written.

ALIMERA SCIENCES, INC., a Delaware corporation

THIS THIRD AMENDMENT TO LEASE AGREEMENT (“Agreement”) dated as of the ___^th day of May 2009, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, having a local regional office at 1170 Peachtree Street, Suite 565, in the city of Atlanta, Georgia 30309 (“Landlord”); and ALIMERA SCIENCES, INC. a Delaware corporation (“Tenant”).

WHEREAS, Landlord and Tenant entered into that certain Office Lease for 6120 Windward Parkway dated May 27, 2003 (the “Original Lease”), and thereafter the First Amendment To Lease (the “First Amendment”) dated July 16, 2004 for certain premises known as Suite 290, containing approximately 14,213 rentable square feet of space (the “Premises”) in the building located at 6120 Windward Parkway, Fulton County, Georgia (the “Building”).

WHEREAS, the Original Lease, the First Amendment, the Second Amendment, and this Third Amendment are collectively referred to as the “Lease”;

WHEREAS, Landlord and Tenant desire to and hereby shall, by this Third Amendment to Lease, modify and amend the terms of the Lease, in the manner and for the purpose herein set forth.

NOW, THEREFORE, for and in consideration of the premises hereto, the keeping and performance of the covenants and agreements hereinafter contained, and for Ten and No/100 Dollars ($10.00) and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant, intending to be legally bound, agree as follows:

1.Defined Terms. All capitalized terms not defined herein shall have the same meaning as set forth in the Lease.

2.Expansion of the Premises. Commencing on September 1, 2009 the Premises shall become 14,462 rentable square feet.

3.Extension of Lease Term. The term of the Lease for the Leased Premises is hereby extended to include the period from September 1, 2009 through May 31, 2010 (the “Second Extension Term”).

4.Rent. The Tenant shall, without demand, deduction or right of offset, pay to the Landlord during the Second Extension Term as rental (herein called “Basic Rent”), the sum of One Hundred Eighty-Eight Thousand, Six Hundred Twenty and 65/100 Dollars ($188,620.65) of lawful money of the jurisdiction in which the Leased Premises are located, in equal monthly installments of Twenty Thousand, Nine Hundred Fifty-Seven and 85/100 Dollars ($20,957.85) each in advance on the first day of each month during the Term, the first payment to be made on the first day of September, 2009. Tenant shall also be obligated to and shall continue to pay Landlord during this period Tenant’s Share of Operating Costs above the Initial Operating Costs, as set forth in Article 3 of the lease.

*Based on a 12-month period.

5.Binding Effect. This Agreement shall be governed by and construed in accordance with the laws of the State of Georgia and shall be binding upon and inure to the benefit of the parties hereto and their respective heirs, successors, representatives and assigns, but always subject, in the case of Tenant, to the limitations on assignment and sublease set forth in the Lease. In the event of any inconsistency or conflict between the terms of this Agreement and of the Lease, the terms hereof shall control. Time is of the essence of all of the terms of this Agreement.

6.    Continued Validity. Except as hereinabove provided, all other terms and conditions of the Lease shall remain unchanged and in full force and effect and are hereby ratified and confirmed by Landlord and Tenant. Tenant hereby acknowledges and agrees that, as of the date hereof, the Lease is subject to no offsets, claims, counterclaims or defenses of any nature whatsoever.

7.Modifications. This Agreement may not be changed, modified, discharged or terminated orally in any manner other than by an agreement in writing signed by Landlord and Tenant or their respective heirs, representatives, successors and permitted assigns.

8.Authority. The persons executing this Agreement on behalf of Landlord and Tenant do hereby personally represent and warrant that they each have the full right and authority to enter into this Agreement.

IN WITNESS WHEREOF, the parties have set their hands and affixed their seals to this Agreement to be effective as of the day and year first above written.

JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.),

wholly owned subsidiary of Manulife Financial Corporation

Per: /s/ Terry L. Gilliam

Name: Terry L. Gilliam

Title: AVP, Regional Director

ALIMERA SCIENCES, INC., a Delaware corporation

By: /s/ Dan Myers

Name: Dan Myers

Title: Pres., CEO

THIS FOURTH AMENDMENT TO LEASE AGREEMENT (“Agreement”) dated as of the 25th day of May 2010, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, having a local regional office at 1170 Peachtree Street, Suite 565, in the city of Atlanta, Georgia 30309 (“Landlord”); and ALIMERA SCIENCES, INC. a Delaware corporation (“Tenant”).

WHEREAS, Landlord and Tenant entered into that certain Office Lease for 6120 Windward Parkway dated May 27, 2003 (the “Original Lease”), and thereafter the First Amendment To Lease (the “First Amendment”) dated July 16, 2004 for certain premises known as Suite 290, containing approximately 14,213 rentable square feet of space (the “Premises”) in the building located at 6120 Windward Parkway, Fulton County, Georgia (the “Building”).

WHEREAS, the Original Lease, the First Amendment, the Second Amendment, the Third Amendment, and this Fourth Amendment are collectively referred to as the “Lease”;

WHEREAS, Landlord and Tenant desire to and hereby shall, by this Fourth Amendment to Lease, modify and amend the terms of the Lease, in the manner and for the purpose herein set forth.

NOW, THEREFORE, for and in consideration of the premises hereto, the keeping and performance of the covenants and agreements hereinafter contained, and for Ten and No/100 Dollars ($10.00) and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant, intending to be legally bound, agree as follows:

1.Defined Terms. All capitalized terms not defined herein shall have the same meaning as set forth in the Lease.

2.Expansion of the Premises. Commencing on September 1, 2009 the Premises became 14,462 rentable square feet, which shall remain in effect for this extension term, and is more particularly described in Exhibit “A” attached hereto and incorporated herein.

3.Extension of Lease Term. The term of the Lease for the Leased Premises is hereby extended to include the period from June 1, 2010 through December 31, 2011 (the “Third Extension Term”).

4.Rent. The Tenant shall, without demand, deduction or right of offset, pay to the Landlord during the Third Extension Term as rental (herein called “Basic Rent”), the annual sum of Two Hundred Fifty-One Thousand, Four Hundred Ninety-Four and 100 Dollars ($251,493.18) of lawful money of the jurisdiction in which the Leased Premises are located, in equal monthly installments of Twenty Thousand, Nine Hundred Fifty-Seven and 85/100 Dollars ($20,957.85) each in advance on the first day of each month during the Term, the first payment to be made on the first day of June, 2010. Tenant shall also be obligated to and shall continue to pay Landlord during this period Tenant’s Share of Operating Costs above the Initial Operating Costs, as set forth in Article 3 of the lease. The Basic Rent shall escalate according to the following schedule:

*Based on a 12-month period.

5.First Right of Refusal. Landlord shall not lease all or any part of the area of the building designated as Suite 220 and marked “First Right of Refusal Space” on Exhibit “B” of approximately 5,323 rentable square feet to any other party without first offering said space to Tenant.

Landlord shall provide written notice to Tenant of Landlord’s desire to rent said Expansion Space to another party and Tenant shall have three (3) days after such notice to indicate in writing its agreement to lease the

Expansion Space at mutually acceptable economic terms and conditions as determined by Landlord and Tenant.

If Tenant does not indicate its willingness to lease the Expansion Space in writing within three (3) days thereafter and execute a lease or lease amendment in form similar to this lease or lease amendment within four (4) days thereafter, Landlord thereafter shall have the right to lease all or part of the Expansion Space to any party and Tenant shall have no right with regard to the Expansion Space.

Tenant shall have no rights under this paragraph whatsoever should Tenant be in default under the terms of this lease.

6.Binding Effect. This Agreement shall be governed by and construed in accordance with the laws of the State of Georgia and shall be binding upon and inure to the benefit of the parties hereto and their respective heirs, successors, representatives and assigns, but always subject, in the case of Tenant, to the limitations on assignment and sublease set forth in the Lease. In the event of any inconsistency or conflict between the terms of this Agreement and of the Lease, the terms hereof shall control. Time is of the essence of all of the terms of this Agreement.

7.Continued Validity. Except as hereinabove provided, all other terms and conditions of the Lease shall remain unchanged and in full force and effect and are hereby ratified and confirmed by Landlord and Tenant. Tenant hereby acknowledges and agrees that, as of the date hereof, the Lease is subject to no offsets, claims, counterclaims or defenses of any nature whatsoever.

8.Modifications. This Agreement may not be changed, modified, discharged or terminated orally in any manner other than by an agreement in writing signed by Landlord and Tenant or their respective heirs, representatives, successors and permitted assigns.

9.Authority. The persons executing this Agreement on behalf of Landlord and Tenant do hereby personally represent and warrant that they each have the full right and authority to enter into this Agreement.

IN WITNESS WHEREOF, the parties have set their hands and affixed their seals to this Agreement to be effective as of the day and year first above written.

(U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation

Per: /s/ Terry L. Gilliam

Name: Terry L. Gilliam

Title: AVP, Regional Director

ALIMERA SCIENCES, INC., a Delaware corporation

Per: /s/ Dan Myers

Name: Dan Myers

Title: Pres., CEO

THIS FIFTH AMENDMENT TO LEASE AGREEMENT (this “Fifth Amendment”) is made and entered into as of the 28^th day of December 2011, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, a Michigan corporation (“Landlord”), and ALIMERA SCIENCES, INC., a Delaware corporation (“Tenant”).

WHEREAS, Rubicon, L.C. (“Original Landlord”) and Tenant entered into that certain Office Lease (the “Original Lease”) dated May 27, 2003, as amended by that certain First Amendment to Lease Agreement (the “First Amendment”) dated July 16, 2004, • as further amended by that certain Second Amendment to Lease Agreement (the “Second Amendment”) dated July 1, 2005, as further amended by that certain Third Amendment to Lease Agreement dated May [sic], 2009, and as further amended by that certain Fourth Amendment to Lease Agreement (the “Fourth Amendment”) dated May 25, 2010 (collectively, as so amended, together with all modifications and supplements thereto, the “Lease”) for certain premises in the building located at 6120 Windward Parkway, Alpharetta, Georgia 30005 (the “Building”), consisting of approximately 14,462 rentable square feet of space on the 2nd floor of the Building known as Suite 290 (the “Premises”);

WHEREAS, Landlord acquired the Building and has succeeded to the interest of Original Landlord as the “Landlord” under the Lease;

WHEREAS, the term of the Lease is scheduled to expire on December 31, 2011, and the parties desire to further extend the term of the Lease to December 31, 2012; and

WHEREAS, Landlord and Tenant desire to evidence the terms of such extension and to amend certain other terms and conditions of the Lease by means of this Fifth Amendment.

NOW, THEREFORE, in consideration of the mutual covenants contained herein, and other good and valuable consideration, the receipt, adequacy and sufficiency of which are hereby acknowledged, the Lease is hereby amended, and the parties hereto do hereby agree as follows:

1.Defined Terms. All terms and definitions, capitalized or otherwise, used herein and not otherwise defined herein shall have the meanings ascribed to them in the Lease.

2.    Extension of Lease Term. The term of the Lease is hereby further extended for a period of twelve (12) months commencing on January 1, 2012 and expiring on December 31, 2012 (the “Fourth Extension Term”), unless sooner terminated pursuant to the terms of the Lease, as amended herein. There shall be no additional renewal or extension terms unless

otherwise mutually agreed to in writing by Landlord and Tenant. Tenant shall remain subject to all the terms and conditions of the Lease, as amended herein, during the Fourth Extension Term.

3.Rent. Tenant shall, without demand, deduction or right of offset, continue to pay to Landlord during the Fourth Extension Term as Base Rent, the annual sum of Two Hundred Sixty-Six Thousand, Eight Hundred Twenty-Three and 90/100 Dollars ($266,823.90), in equal monthly installments of Twenty-Two Thousand Two Hundred Thirty-Five and 33/100 Dollars ($22,235.33) each in advance on the first day of each month during the Fourth Extension Term, the first payment to be made on January 1, 2012. Tenant shall also be obligated to and shall continue to pay Landlord during the Fourth Extension Term, Tenant’s Share of increases in Taxes and Operating Expenses over $356,040.00, as set forth in Article 1(b) of the Original Lease, as amended by Paragraph 5 (Taxes and Operating Expenses) of the Second Amendment.

4.Acceptance of Premises. Tenant hereby accepts the Premises in its “AS IS” condition during the Fourth Extension Term and acknowledges and agrees Landlord shall have no obligation to construct any tenant improvements to the Premises or make any alterations or additions thereto, and Landlord shall have no obligation to provide any tenant improvement allowance, rent abatement, credit, set-off, or other concession to Tenant.

(a)Notwithstanding anything to the contrary contained in the Lease, provided Tenant is not in an event of default under the Lease (as amended herein) regardless of any notice or cure period, Tenant shall have a first option (the “First Termination Option”) to terminate the Lease, effective as of June 30, 2012 (the “First Termination Date”), by providing Landlord with written notice of such First Termination Option election (the “First Termination Notice”). Such First Termination Notice shall be effective only if it is given to Landlord on or before March 31, 2012 (the “First Termination Notice Deadline”); accordingly, if Tenant has not given its First Termination Notice to Landlord prior to the First Termination Notice Deadline, this First Termination Option shall expire and be of no further force or effect, and Tenant shall have no right or option to terminate the Lease pursuant to this subparagraph (a) of this Paragraph 5 at any time after the First Termination Notice Deadline. If Tenant complies with this Paragraph 5 (including subparagraph (c) hereof), Tenant shall continue to be liable for its obligations under the Lease to and through the First Termination Date, including, without limitation, additional rent that accrues pursuant to the terms of the Lease, with all of such obligations surviving the early termination of the Lease.

(b)Notwithstanding anything to the contrary contained in the Lease, provided Tenant is not in an event of default under the Lease (as amended herein) regardless of any notice or cure period, Tenant shall have a second option (the “Second Termination Option”) to terminate the Lease, effective as of September 30, 2012 (the “Second Termination Date”), by providing Landlord with written notice of such Second Termination Option election (the “Second Termination Notice”). Such Second Termination Notice shall be effective only if it is given to Landlord on or before June 30, 2012 (the “Second Termination Notice Deadline”); accordingly, if Tenant has not given its Second Termination Notice to Landlord prior to the Second Termination

Notice Deadline, this Second Termination Option shall expire and be of no further force or effect, and Tenant shall have no right or option to terminate the Lease pursuant to this Paragraph 5 at any time after the Second Termination Notice Deadline. If Tenant complies with this Paragraph 5 (including subparagraph (c) hereof), Tenant shall continue to be liable for its obligations under the Lease to and through the Second Termination Date, including, without limitation, additional rent that accrues pursuant to the terms of the Lease, with all of such obligations surviving the early termination of the Lease.

(c)As a condition precedent to a termination of the Lease pursuant to the provisions of this Paragraph 5, simultaneously with Tenant’s delivery of either the First Termination Notice or the Second Termination Notice, as applicable, Tenant must deliver to Landlord the Termination Fee (as hereinafter defined). As used herein, the “Termination Fee” shall mean an amount equal to the unamortized portion (amortized with an interest rate of ten percent (10%) per annum) as of the applicable Termination Date of any leasing commissions paid by Landlord in connection with this Fifth Amendment. It is hereby acknowledged that any such amount required to be paid by Tenant in connection with such early termination is not a penalty but a reasonable pre-estimate of the damages which would be incurred by Landlord as a result of such early termination of the Lease (which damages are impossible to calculate more precisely) and, in that regard, constitutes liquidated damages with respect to such loss.

(d)The rights granted to Tenant under this Paragraph 5 are personal to the named Tenant, and in the event of any assignment of the Lease or sublease by Tenant, the First Termination Option and the Second Termination Option shall thenceforth be void and of no further force or effect. Tenant’s rights under this Paragraph 5 shall be effective only if Tenant is not in default (regardless of any notice and/or cure period) under the Lease, as amended hereby, nor has any event occurred which with the giving of notice or the passage of time, or both, would constitute an event of default under the Lease (regardless of any notice and/or cure period), as amended hereby, either at the time of the delivery of the First Termination Notice or the Second Termination Notice, or as of the First Termination Date or the Second Termination Date.

6.Deleted Provisions. As of date of this Fifth Amendment, the Lease is hereby amended by deleting the following provisions in their entirety:

(a)Paragraph No. 2 of the Rider contained in Exhibit “B” to the Original Lease;

(b)Paragraph No. 7 of the First Amendment;

(c)Paragraph No. 7 of the Second Amendment and Exhibit B to the Second Amendment; and

(d)Paragraph No. 5 of the Fourth Amendment and Exhibit B to the Fourth Amendment.

7.    Brokers. Tenant represents and warrants to Landlord that neither it nor its officers or agents nor anyone acting on its behalf has dealt with any real estate broker other than Lavista Associates, Inc. (“Landlord’s Broker’), which represented Landlord, and ICON Commercial Interests, LLC (“Tenant’s Broker’), which represented Tenant, in the negotiating and making of

this Fifth Amendment, and Tenant agrees to indemnify and hold Landlord, its agents, employees, partners, directors, shareholders and independent contractors harmless from all liabilities, costs, demands, judgments, settlements, claims, and losses, including reasonable attorneys’ fees and costs, incurred by Landlord in conjunction with any such claim or claims of any other broker or brokers claiming to have interested Tenant in the Building or Premises or claiming to have caused Tenant to enter into this Fifth Amendment. Landlord agrees to pay the commission due to Landlord’s Broker and Tenant’s Broker in connection with this Fifth Amendment pursuant to separate written commission agreements.

(a)Notices to Landlord. Landlord acknowledges that its current address for any notice, demands, requests, consents or approvals from Tenant to Landlord under the Lease, as amended herein, is as follows:

John Hancock Life Insurance Company (U.S.A.)

c/o Manulife Financial

Atlanta Real Estate Office

1170 Peachtree Street, Suite 565

Atlanta, Georgia 30309

Attn: Lease Administration

(b)Rent Payment Address. Landlord acknowledges that its current address for rent payments under the Lease, as amended herein, is as follows:

John Hancock Life Insurance Company (U.S.A.)

c/o Manulife Financial

Department A

P.O. Box 5147

Buffalo, New York ###-###-####

Attn: Real Estate Division

9.No Defaults. Tenant hereby agrees that there are, as of the date hereof, regardless of the giving of notice or the passage of time, or both, no defaults or breaches on the part of Landlord or Tenant under the Lease.

10.Headings. The headings used herein are provided for convenience only and are not to be considered in construing this Fifth Amendment,

11.    Entire Agreement. This Fifth Amendment represents the entire agreement between the parties with respect to the subject matter hereof. Landlord and Tenant agree that there are no collateral or oral agreements or understandings between them with respect to the Premises or the Building other than the Lease and this Fifth Amendment. This Fifth Amendment supersedes all prior negotiations, agreements, letters or other statements with respect to Tenant’s further extension of the term of the Lease

12.Binding Effect. This Fifth Amendment shall not be valid and binding on Landlord and Tenant unless and until it has been completely executed by and delivered to both parties.

13.Confirmation of Lease. Except as expressly amended and modified by this Fifth Amendment, the Lease shall otherwise remain unmodified and in full force and effect, and the parties hereto hereby ratify and confirm the same. To the extent of any inconsistency between the Lease and this Fifth Amendment, the terms of this Fifth Amendment shall control,

IN WITNESS WHEREOF, the undersigned parties have duly executed this Fifth Amendment under seal as of the day and year first above written.

COMPANY (U.S.A.), a wholly owned

subsidiary of Manulife Financial

Corporation

By: /s/ Terry L. Gilliam

Terry L. Gilliam

Managing Director, Southeastern US

Manulife Financial

Date: December 28, 2011

ALIMERA SCIENCES, INC.,

a Delaware corporation

By: /s/ Richard S. Eiswirth, Jr.

Print Name: Richard S. Eiswirth, Jr.

Title: Chief Operating Officer and Chief Financial Officer

Date: December 12, 2011

THIS SIXTH AMENDMENT TO LEASE AGREEMENT (this “Sixth Amendment”) is made and entered into as of the 6^th day of November 2012, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, a Michigan corporation (“Landlord”), and ALIMERA SCIENCES, INC., a Delaware corporation (“Tenant”).

WHEREAS, Rubicon, L.C. (“Original Landlord”) and Tenant entered into that certain Office Lease (the “Original Lease”) dated May 27, 2003, as amended by that certain First Amendment to Lease Agreement dated July 16, 2004, as further amended by that certain Letter Agreement dated March 1, 2005, as further amended by that certain Second Amendment to Lease Agreement (the “Second Amendment”) dated July 1, 2005, as further amended by that certain Third Amendment to Lease Agreement dated May [sic], 2009, as further amended by that certain Fourth Amendment to Lease Agreement dated May 25, 2010, and as further amended by that certain Fifth Amendment to Lease Agreement (the “Fifth Amendment”) dated December 28, 2011 (collectively, as so amended, together with all modifications and supplements thereto, the “Lease”) for certain premises in the building located at 6120 Windward Parkway, Alpharetta, Georgia 30005 (the “Building”), consisting, of approximately 14,462 rentable square feet of space on the 2^nd floor of the Building known as Suite 290 (the “Premises”):

WHEREAS, Landlord acquired the Building and has succeeded to the interest of Original Landlord as the “Landlord” under the Lease;

WHEREAS, the term of the Lease is scheduled to expire on December 31, 2012, and the parties desire to further extend the term of the Lease to January 31, 2015; and

WHEREAS, Landlord and Tenant desire to evidence the terms of such extension and to amend certain other terms and conditions of the Lease by means of this Sixth Amendment.

NOW, THEREFORE, in consideration of the mutual covenants contained herein, and other good and valuable consideration, the receipt, adequacy and sufficiency of which are hereby acknowledged, the Lease is hereby amended, and the parties hereto do hereby agree as follows;

1.Defined Terms. All terms and definitions, capitalized or otherwise, used herein and not otherwise defined herein shall have the meanings ascribed to them in the Lease.

2.    Extension of Lease Term. The term of the Lease is hereby further extended for a period of twenty-five (25) months commencing on January 1, 2013 (the “Fifth Extension Term Commencement Date”) and expiring at midnight on January 31, 2015 (the “Fifth Extension Term”), unless sooner terminated pursuant to the terms of the Lease, as amended herein. As of

the Fifth Extension Term Commencement Date, there shall be no additional renewal or extension terms unless otherwise mutually agreed to in writing by Landlord and Tenant. Tenant shall remain subject to all the terms and conditions of the Lease, as amended herein, during the Fifth Extension Term.

3.Base Rent. During the Fifth Extension Term, Base Rent for the Premises shall be as follows:

*Base Rent Per Annum is Monthly Installments of Base Rent multiplied by 12.

Notwithstanding the foregoing rent schedule, so long as Tenant is not in an event of default under the Lease, as amended herein, beyond any applicable notice and cure period, all Rent (including, additional rent) for the first (1^st) month of this Fifth Extension Term (the “Abatement Period”) shall be abated (the “Abatement”). Notwithstanding any other remedy set forth in the Lease, as amended herein, if Tenant defaults at any time during the Fifth Extension Term such that Landlord terminates the Lease, as amended herein, or Tenant’s possession under the Lease, the unamortized portion of the foregoing Abatement shall be cancelled and all Rent which would have otherwise been due during such period shall be immediately due and payable by Tenant to Landlord as a component of Landlord’s damages under the Lease, as amended herein,

4.Taxes and Operating Expenses. In addition to the Base Rent, as previously set forth in the Lease, the parties agree that Tenant’s Share of increases in Taxes and Operating Expenses will now be paid over the actual Taxes and Operating Expenses incurred in the Base Year 2013 rather than over an expense stop.

5.    Acceptance of Premises. Tenant hereby accepts the Premises in its “AS IS” condition during the Fifth Extension Term and acknowledges and agrees Landlord shall have no obligation to construct any tenant improvements to the Premises or make any alterations or additions thereto, and Landlord shall have no obligation to provide any tenant improvement allowance, credit, set-off, or other concession to Tenant, except as set forth herein. Landlord shall provide to Tenant as a tenant improvements allowance up to Four Dollars (S4.00) per rentable square foot of the Premises (i.e., up to $57,848.00) (the “Allowance”), which shall be applied by Landlord to its construction management fee and to the following work in and to the Premises (the “Work”): (a) to steam clean the carpet in the Premises, (b) to repaint the Premises. using materials and colors approved by Landlord, and (c) such other work as may be approved by Landlord (subject to Landlord’s possible requirement of a work letter and construction drawings depending upon the nature and scope of such work), Landlord will coordinate the Work and will receive a construction management fee of five percent (5%) of the cost of the Work, which fee will be paid from the Allowance. Tenant will be solely responsible

for moving, Tenant’s furniture, trade fixtures and equipment (“FF&E”) as reasonably necessary to accommodate the Work, the costs for which may be paid from the Allowance, if available. If the contractor performing the Work is responsible for moving the FF&E, the costs thereof will be paid by Landlord from the Allowance directly to the contractor. If Tenant does not engage the contractor to move its FF&E, any costs associated therewith may be paid from the Allowance, if available, within thirty (30) days of Landlord’s receipt of paid invoices or receipts. Tenant will reasonably cooperate with Landlord to accommodate performance of the Work, and Landlord will reasonably cooperate with Tenant to minimize the disruption to Tenant’s operations caused by the performance of the Work. However, Tenant will not be entitled to any abatement or reduction of Rent by reason of any interruption to Tenant’s operations caused by the performance of the Work. Tenant agrees that Landlord will not be liable in any way for any injury, loss, or damage which may occur to any of Tenant’s property placed or installations made in the Premises during the performance of the Work, the same being at Tenant’s sole risk. Tenant shall be responsible for all costs of the Work in excess of the Allowance, if any. Any unused portion of the Allowance may be applied toward the cost of FF&E for the Premises so long. as Landlord is provided with invoices detailing such costs and appropriate detail of backup satisfactory to Landlord. Landlord agrees, upon receipt of such written evidence (including paid invoices) of such costs, to reimburse Tenant for the FF&E cost up to the remaining amount of the Allowance. Any unused portion of the Allowance must be utilized by or on behalf of Tenant for the purposes set forth herein on or before March 31, 2013. If not. Landlord will be entitled to retain any remaining balance of the Allowance and Tenant will forfeit all rights with respect thereto. In no event shall any portion of the Allowance be used toward the payment of or as a credit or set-off against any Rent hereunder or under the Lease.

6.Deleted Provision. As of the date of this Sixth Amendment, the Lease is hereby amended by deleting Paragraph 5 of the Fifth Amendment in its entirety.

7.Brokers. Tenant represents and warrants to Landlord that neither it nor its officers or agents nor anyone acting on its behalf has dealt with any real estate broker other than Lavista Associates, Inc. (“Landlord’s Broker”), which represented Landlord. and ICON Commercial Interests, LLC (“Tenant’s Broker”), which represented Tenant, in the negotiating and making of this Sixth Amendment, and Tenant agrees to indemnify and hold Landlord, its agents, employees, partners, directors, shareholders and independent contractors harmless from all liabilities, costs, demands, judgments, settlement, claims, and losses, including reasonable attorneys’ fees and costs, incurred by Landlord in conjunction with any such claim or claims of any other broker or brokers claiming to have interested Tenant in the Building or Premises or claiming to have caused Tenant to enter into this Sixth Amendment. Landlord agrees to pay the commission due to Landlord’s Broker and Tenant’s Broker in connection with this Sixth Amendment pursuant to separate written commission agreements.

8.No Defaults. Tenant hereby agrees that to the best of its knowledge, there are, as of the date hereof, regardless of the giving of notice or the passage of time, or both, no defaults or breaches on the part of Landlord or Tenant under the Lease.

9.    Headings. The headings used herein are provided for convenience only and are not to be considered in construing this Sixth Amendment.

10.Entire Agreement. This Sixth Amendment represents the entire agreement between the parties with respect to the subject matter hereof. Landlord and Tenant agree that there are no collateral or oral agreements or understandings between them with respect to the Premises or the Building other than the Lease and this Sixth Amendment. This Sixth Amendment supersedes all prior negotiations, agreements, letters or other statements with respect to Tenant’s further extension of the term of the Lease.

11.Binding Effect. This Sixth Amendment shall not be valid and binding on Landlord and Tenant unless and until it has been completely executed by and delivered to both parties.

12.Authorization. The person signing this Sixth Amendment on behalf of Tenant hereby represents and warrants that (i) he/she is authorized to execute this Sixth Amendment on behalf of Tenant, (ii) he/she possesses the requisite power and authority to bind Tenant to the terms and provisions hereof, (iii) Tenant has taken all actions necessary to authorize the execution, delivery and performance of this Sixth Amendment by Tenant, and (iv) Tenant has been duly organized and is qualified or authorized to do business in the State in which the Premises is located. Furthermore, Tenant agrees to take any and all necessary action to keep its existence as an entity in good standing throughout the term of the Lease as extended herein, in the State in which Tenant has been organized as well as to remain qualified to do business within the State in which the Premises are located.

13.Confirmation of Lease. Except as expressly amended and modified by this Sixth Amendment, the Lease shall otherwise remain unmodified and in full force and effect, and the parties hereto hereby ratify and confirm the same. To the extent of any inconsistency between the Lease and this Sixth Amendment the terms of this Sixth Amendment shall control.

IN WITNESS WHEREOF, the undersigned parties have duly executed this Sixth Amendment under seal as of the day and year first above written.

By: /s/ Terry L. Gilliam

Terry L. Gilliam

Managing Director, Southeastern US

Manulife Financial

Date: October 6^th, 2012

ALIMERA SCIENCES, INC.,

a Delaware corporation

By: /s/ Richard S. Eiswirth, Jr.

Print Name: Richard S. Eiswirth, Jr.

Title: Chief Operating Officer and Chief Financial Officer

Date: October ___, 2012

THIS AMENDED AND RESTATED SEVENTH AMENDMENT TO LEASE AGREEMENT (this “Amendment”) is made and entered into as of the 14^th day of August 2014, by and between JOHN HANCOCK LIFE INSURANCE COMPANY (U.S.A.), a wholly owned subsidiary of Manulife Financial Corporation, a Michigan corporation (“Landlord”), and ALIMERA SCIENCES, INC. a Delaware corporation (“Tenant”).

WHEREAS, Rubicon, L.C. (“Original Landlord”) and Tenant entered into that certain Office Lease (the “Original Lease”) dated May 27, 2003, as amended by that certain First Amendment to Lease Agreement by and between The Manufacturers Life Insurance Company (“Interim Landlord”), as successor-in-interest to Original Landlord, and Tenant dated July 16, 2004, as further amended by that certain Letter Agreement (the “Letter Agreement”) dated March 1, 2005, as further amended by that certain Second Amendment to Lease Agreement by and between Landlord, as successor-in-interest to Interim Landlord, and Tenant (the “Second Amendment”) dated July 1, 2005, as further amended by that certain Third Amendment to Lease Agreement dated May [sic], 2009, as further amended by that certain Fourth Amendment to Lease Agreement dated May 25, 2010, as further amended by that certain Fifth Amendment to Lease Agreement dated December 28, 2011, and as further amended by that certain Sixth Amendment to Lease Agreement (the “Sixth Amendment”) dated November 6, 2012 (collectively, as so amended, the “Lease”), for certain premises in the building known as and located at 6120 Windward Parkway, Alpharetta, Georgia 30005 (the “Building”), consisting of approximately 14,462 rentable square feet of space located on the 2^nd floor of the Building and known as Suite 290, which premises are more particularly described in the Lease (the “Original Premises”);

WHEREAS, Landlord and Tenant entered into that certain Seventh Amendment to Lease Agreement dated July 16, 2014, amending the Lease by expanding the Premises and extending the Term of the Lease (the “Prior Seventh Amendment”);

WHEREAS, Landlord and Tenant desire to amend and restate the Prior Seventh Amendment in its entirety pursuant to the terms hereof.

NOW, THEREFORE, in consideration of the mutual covenants contained herein, and other good and valuable consideration, the receipt, adequacy and sufficiency of which are hereby acknowledged, the Lease is hereby amended, and the parties hereto do hereby agree as follows:

1.Recitals; Capitalized Terms. The recitals set forth herein above are incorporated herein as if restated in their entireties. All capitalized terms used herein and not otherwise defined herein shall have the meanings ascribed to them in the Lease.

2.    Extension of Lease Term. The Term of the Lease is hereby recast and extended for a period of eighty-four (84) months, plus any partial month occasioned by the Effective Date (as hereinafter defined) occurring on any day other than the first (1^st) day of a calendar month (the “Sixth Extension Term”), commencing on that date (the “Effective Date”) which is the earlier of (i) September 27, 2014, and (ii) the business day immediately succeeding the date Landlord receives the Contingency Satisfaction Notice (as defined in Paragraph 13 below), and expiring at

midnight on the last day of the eighty-fourth (84^th) full calendar month beginning on or after the Effective Date, unless sooner terminated or extended pursuant to the terms of the Lease, as amended herein. All references in the Lease to the Term shall hereafter be deemed to include the Sixth Extension Term. Tenant shall remain subject to all the terms and conditions of the Lease, as amended herein, during the Term, as extended by the Sixth Extension Term. Except as set forth in Paragraph 11 below, there shall be no additional renewal or extension terms unless otherwise mutually agreed to in writing by Landlord and Tenant and therefore, all prior renewal or extension options, if any, are hereby terminated and deemed null and void and are hereby deleted in their entireties (except the heading) and replaced with the words “Intentionally Deleted”.

3.Expansion; Grant of Expansion Space. As of the Effective Date, Landlord agrees to lease to Tenant and Tenant agrees to lease from Landlord, for the entire Term, as extended herein and as may be further extended, and subject to and in accordance with the terms of the Lease, as amended by this Amendment, an additional 3,632 rentable square feet of space on the first (1^st) floor of the Building known as Suite 180, as shown on Exhibit A attached hereto and by this reference made a part hereof (the “Expansion Space”). As of the Effective Date: (a) the Expansion Space shall be subject to all of the terms and conditions of the Lease, as amended herein, for the entire Term, as extended herein and as may be further extended; (b) all references in the Lease to the “Premises” shall be deemed to include the Original Premises and the Expansion Space; and (c) the total rentable square feet of space leased pursuant to the Lease shall be 18,094 rentable square feet on the 1^st and 2^nd floors of the Building. Tenant’s notice address shall remain as set forth in Section 18 of the Original Lease.

4.Base Rent. From and after the Effective Date, Base Rent with respect to the Premises, including the Expansion Space, shall be as follows (prorated for any partial month pursuant to the terms of the Lease):

Notwithstanding the foregoing rent schedule, so long as Tenant is not in default hereunder beyond any applicable notice and cure period, all Rent (including Additional Rent, as hereinafter defined) for the initial eight (8) months of the Sixth Extension Term commencing on the Effective Date (the “Abatement Period”) shall be abated (the “Abatement”). In addition to, and not in lieu of, any other remedy set forth in the Lease, as amended herein, if Tenant fails to take possession of the Expansion Space or otherwise defaults at any time during the Sixth Extension Term such that Landlord terminates the Lease, as amended herein, or Tenant’s possession under the Lease, as

amended herein, the unamortized portion of the foregoing Abatement (amortized over the period commencing upon expiration of the Abatement Period and running through and including the last day of the Sixth Extension Term) shall be cancelled and all Rent which would have otherwise been due during such period shall be immediately due and payable by Tenant to Landlord as a component of Landlord’s damages under the Lease, as amended herein.

(a)Base Year. During the Term, as extended herein, Tenant shall continue to pay Tenant’s Share (determined in accordance with Paragraph 5(b) herein below) of Taxes and Operating Expenses over those incurred in a Base Year (in lieu of an expense stop), as set forth in Paragraph 4 of the Sixth Amendment; provided, however, that from and after the Effective Date, the Base Year shall be deemed to be calendar year 2014. Furthermore, with respect to the calculation of Operating Expenses under the Lease, as amended herein, (i) the “gross up” provisions set forth in the Letter Agreement (wherein all references to “Operating Costs” shall hereafter be deemed to refer to “Operating Expenses” and all references to “Fiscal Period” shall hereafter be deemed to refer to “calendar year”) and (ii) the cap on “controllable” Operating Expenses set forth in Paragraph 5 of the Second Amendment, which shall henceforth be calculated on a cumulative, compounding basis notwithstanding anything in the Second Amendment to the contrary, shall both continue in full force and effect through the Term, as extended by the Sixth Extension Term and as may be further extended.

(b)Tenant’s Share. As of the Effective Date, the second (2^nd) grammatical paragraph of Section 1(b) of the Original Lease is hereby deleted in its entirety and replaced with the following:

“Tenant’s Share” shall be determined by dividing the rentable square footage of the Premises by the rentable square footage of the Building, subject to adjustment (as determined solely by Landlord and notified to Tenant in writing) for physical increases or decreases in the total rentable square footage of the Building, provided that the total rentable square footage of the Building and the Premises shall exclude areas designated (whether or not rented) for parking and for storage.”

Accordingly, as of the Effective Date, Tenant’s Share is deemed to be thirty-six and eighty-three hundredths percent (36.83%).

6.    Security Deposit. As a further inducement for Landlord to enter into this Amendment, contemporaneously with the execution of this Amendment by Tenant, Tenant shall deposit with Landlord the amount of One Thousand Nine Hundred Two and 72/100 Dollars ($1,902.72), which shall be added to Tenant’s current security deposit of $23,730.45, for a total security deposit of Twenty-Five Thousand Six Hundred Thirty-Three and 17/100 Dollars ($25,633.17) (the “Security Deposit”), to be held and applied by Landlord in accordance with the terms of Section 22 of the Original Lease. All other terms and conditions of the Lease shall continue to apply to the Security Deposit, as so increased.

7.Signage. As of the Effective Date, Landlord hereby agrees to provide and install, at Tenant’s sole cost and expense, but subject to the application of the Allowance, the Expansion Space entry signage, and to update Tenant’s Building directory signage.

8.Parking. Notwithstanding anything in the Lease to the contrary, from and after the Effective Date, Tenant shall have the right to use up to eighty (80) unreserved parking spaces in the parking facilities serving the Building, all of which shall be available to Tenant on an unassigned, “first come-first served” basis during the Term (the “Permitted Parking Spaces”). Tenant shall not utilize any parking spaces other than the Permitted Parking Spaces. Tenant and its employees and invitees shall not park in any spaces reserved for another tenant and marked for reserved use. Landlord has and reserves the right to alter the methods used to control parking and the right to establish such controls and rules and regulations (such as parking stickers to be affixed to vehicles) regarding parking that Landlord may deem desirable. Without liability, Landlord will have the right to tow or otherwise remove vehicles improperly parked, blocking ingress or egress lanes, or violating parking rules, at the expense of the offending tenant and/or owner of the vehicle. Tenant’s right to use the parking facilities pursuant to the Lease, as amended herein, are subject to the following conditions: (i) Landlord has no obligation to provide a parking attendant and Landlord shall have no liability on account of any loss or damage to any vehicle or the contents thereof, Tenant hereby agreeing to bear the risk of loss for same; and (ii) if and when so requested by Landlord, Tenant shall furnish Landlord with the license plate numbers of any vehicles of Tenant and its employees and invitees using the parking facilities.

(a)Tenant hereby accepts the Premises, as expanded herein, in its “AS IS,” “WHERE IS” condition, WITH ALL FAULTS, and without any representations or warranties (express or implied) whatsoever, during the Term, as extended by the Sixth Extension Term, and hereby acknowledges and agrees Landlord shall have no obligation to construct any tenant improvements to the Premises, and Landlord shall have no obligation to provide any tenant improvement allowance, credit, set-off, or other concession to Tenant, except as expressly set forth in Paragraph 9(b) below.

(b)    Landlord shall provide to Tenant as a tenant improvements allowance up to Twelve and No/100 Dollars ($12.00) per rentable square foot of the Premises, as expanded herein (i.e., up to $217,128.00 in the aggregate) (the “Allowance”), which may be applied to all construction/alteration costs as follows (collectively, the “Construction Costs”) and construction management fees: (i) for certain improvements in and to the Premises based upon a mutually agreeable space plan (the “Improvements”), (ii) design/architecture costs, (iii) construction, (iv) engineering, (v) professional fees, (vi) permitting, if any, and (vii) soft costs for the construction of or alterations to the Premises. Tenant shall be responsible for all Construction Costs in excess of the Allowance, if any, and shall reimburse Landlord for such difference promptly upon receipt of invoices for the same. Additionally, if, prior to commencement of construction, the parties anticipate that the total Construction Costs shall be more than the Allowance (a “Shortfall”), Tenant shall pay to Landlord such Shortfall prior to the commencement of the Improvements. Landlord or its designee shall serve as construction manager (“Construction Manager”). The Construction Manager, on behalf of Landlord and Tenant, shall (1) coordinate architectural and engineering planning; (2) solicit bids from at least three (3) qualified contractors and conduct any

permitting processes; (3) award the bid to the lowest qualified general contractor(s)/subcontractor(s); (4) supervise the construction of the Improvements in the Premises, and (5) pay the Allowance to all contractors and subcontractors directly. The Construction Manager shall be paid a fee of five percent (5%) of the Construction Costs with such fee to be deducted from the Allowance by Landlord. If the entire Allowance is not exhausted in constructing the Improvements, then, subject to the terms and provisions of this Paragraph 9(b) and so long as Tenant is not in an event of default beyond any applicable notice and cure period, such unused and remaining portion up to, but in no event in excess of, Fifty Thousand and No/100 Dollars ($50,000.00) (the “Excess Allowance”) may be used to reimburse Tenant for reasonable costs actually incurred by Tenant with respect to the acquisition and installation of furniture and telecommunications equipment and cabling specifically for the Premises, subject to the terms of this Paragraph 9(b). The Excess Allowance, if any, shall be disbursed to Tenant within sixty (60) days after Tenant’s request for same (but, in any event, any such request may not be delivered until after the Effective Date), together with copies of invoices along with paid receipts evidencing such costs to the reasonable satisfaction of Landlord. Any unused portion of the Allowance, including the Excess Allowance, must be utilized by Tenant for the purposes set forth herein within six (6) months from the Effective Date. If not, Landlord will be entitled to retain any remaining balance of the Allowance and Tenant will forfeit all rights with respect thereto. Tenant acknowledges that the Improvements in the Premises shall be performed while Tenant is in occupancy of the Premises and that Landlord shall use reasonable efforts not to interfere with Tenant’s use of the Premises during the performance of the construction of or any alterations to the Premises, but that some such interference may occur and shall not be a default by Landlord under the Lease. Prior to commencement of the Improvements, the Construction Manager will coordinate the schedule for the completion of the Improvements with Tenant (or Tenant’s designee). Landlord shall not be required to incur overtime costs and expenses in performing the Improvements in the Premises.

(c)Landlord and Tenant acknowledge and agree that the Improvements shall include a renovation of the entrance door to the Premises, such that the Premises entryway is full height and compliant with all applicable laws, codes, and ordinances, including but not limited to the Americans with Disabilities Act and any other law pertaining to disabilities and architectural barriers (collectively, “ADA”).

10.    Termination Option. Notwithstanding anything to the contrary contained in the Lease, as amended herein, Tenant shall have the one-time option (the “Termination Option”) to terminate the Lease, as amended herein, effective as of the last day of the sixtieth (60^th) full calendar month of the Sixth Extension Term (the “Termination Date”), by providing Landlord with written notice of such Termination Option election (the “Termination Notice”). Such Termination Notice shall be effective only if it is given to Landlord on or before the last day of the fifty-first (51^st) full calendar month of the Sixth Extension Term (the “Termination Notice Deadline”); accordingly, if Tenant has not given its Termination Notice to Landlord prior to the Termination Notice Deadline, this Termination Option shall expire and be of no further force or effect, and Tenant shall have no right or option to terminate this Lease pursuant to this Paragraph 10 at any time after the Termination Notice Deadline. As a condition precedent to any termination of this Lease pursuant to the provisions of this Paragraph 10, in addition to Tenant’s delivery of its Termination Notice, Tenant must have delivered to Landlord with its Termination Notice an amount as a termination fee (collectively, the “Termination Fee”) equal to the sum of (i) one (1) months of Base Rent and Additional Rent that would have been in effect during the month

following the Termination Date had the Lease not been terminated, plus (ii) all unamortized Transaction Costs, as hereinafter defined, incurred in connection with this Amendment and incurred by Landlord for any other expansion space leased by Tenant, all amortized using an interest rate of eight percent [8%] per annum over the applicable time period as further described below, and (iii) legal fees incurred by Landlord in connection with this Amendment and any future amendment whereby Tenant is leasing additional space. “Transaction Costs” shall include generally, without limitation, any tenant improvement allowance, turnkey construction costs, leasing commissions, free rent and cash allowances or similar costs and expenses provided to Tenant or incurred by Landlord. For purposes of this Amendment, Transaction Costs will include the Allowance, the Abatement, and the leasing commissions incurred in connection with the Premises, as expanded herein, which shall be amortized over the period commencing on the expiration of the Abatement Period and running through and including the last day of the Sixth Extension Term. With respect to any future expansion space, the Transaction Costs will be amortized over the period commencing on the date Tenant commences paying rent for such expansion space through the expiration date of Tenant’s lease of such expansion space. It is hereby acknowledged that any such amount required to be paid by Tenant in connection with such early termination is not a penalty but a reasonable pre-estimate of the damages which would be incurred by Landlord as a result of such early termination of this Lease (which damages are impossible to calculate more precisely) and, in that regard, constitutes liquidated damages with respect to such loss. Tenant shall continue to be liable for its obligations under the Lease, as amended herein, to and through the Termination Date, including, without limitation, Additional Rent that accrues pursuant to the terms of this Lease, with all of such obligations surviving the early termination of the Lease. The rights granted to Tenant under this Paragraph 10 are personal to the named Tenant, and in the event of any assignment of this Lease or sublease by Tenant, this Termination Option shall thenceforth be void and of no further force or effect. Tenant’s rights under this Paragraph 10 shall be effective only if Tenant is then current in the payment of all Rent then due under the Lease, and no event of default exists, both at the time of the delivery of the Termination Notice and as of the Termination Date. Notwithstanding anything herein to the contrary, this Termination Option shall be null and void and of no further force or effect upon the giving of any Extension Notice, as defined in Paragraph 11 below.

11.    Option to Extend. Subject to the rights of existing tenants in the Building as of the date of this Amendment and so long as the Lease, as amended herein, is in full force and effect and Tenant is not in default beyond applicable notice and cure periods in the performance of any of the covenants or terms and conditions of the Lease, as amended, at the time of notification to Landlord or at the time of commencement of the Seventh Extension Term, as that term is hereinafter defined, Tenant shall have the option (the “7th Amendment Extension Option”) to extend the Term, as extended herein by the Sixth Extension Term, for the entire Premises, as expanded herein by the Expansion Space, for one (1) additional period of five (5) years (the “Extension Term”), at the Prevailing Market Rate, as that term is hereinafter defined, subject to the terms and conditions set forth in this Paragraph 11. Tenant shall provide Landlord with written notice on or before the last day of the seventy-fifth (75^th) full calendar month of the Sixth Extension Term, but in no event before the last day of the seventy-second (72^nd) full calendar month of the Sixth Extension Term, of its exercise of the 7^th Amendment Extension Option (the “Extension Notice”). Landlord shall provide Tenant with a written proposal setting forth its determination of the Prevailing Market Rate to extend the Term within thirty (30) days of receipt of such Extension Notice. Tenant shall have ten (10) days from its receipt of Landlord’s proposal

to either accept such proposal or to not extend the Term. The “Prevailing Market Rate” shall mean the then prevailing market rate for lease renewals and extensions in the Building and in similar buildings in the vicinity of the Building comparable to the Lease, as amended hereby, and the Premises, which shall be determined by Landlord in its sole but reasonable discretion. If Landlord and Tenant are unable to reasonably agree upon the Prevailing Market Rate within such 10-day period after Tenant’s receipt of Landlord’s proposal, then Tenant’s exercise of the 7^th Amendment Extension Option shall be null and void and of no further force or effect. Notwithstanding anything herein to the contrary, this 7^th Amendment Extension Option shall be null and void and of no further force or effect upon the giving of any Termination Notice, as defined in Paragraph 10 above.

12.Landlord’s Notice Address. From and after the date hereof and notwithstanding anything to the contrary in the Lease, Landlord acknowledges that its current address for notices under the Lease is as follows:

John Hancock Life Insurance Company (U.S.A.)

c/o Manulife Financial

Atlanta Real Estate Office

1170 Peachtree Street, Suite 1865

Atlanta, Georgia 30309

Attn: Property Manager

13.    CONTINGENCY; TERMINATION OF AMENDMENT. NOTWITHSTANDING ANYTHING IN THIS AMENDMENT TO THE CONTRARY, TENANT SHALL HAVE THE RIGHT TO VOID THIS AMENDMENT (THE “CONTINGENCY”) BY GIVING LANDLORD WRITTEN NOTICE (THE “CONTINGENCY TERMINATION NOTICE”) ON OR BEFORE SEPTEMBER 26, 2014 (THE “CONTINGENCY DEADLINE”); ACCORDINGLY, IF TENANT HAS NOT GIVEN ITS CONTINGENCY TERMINATION NOTICE TO LANDLORD PRIOR TO THE CONTINGENCY DEADLINE, THIS CONTINGENCY SHALL EXPIRE AND BE OF NO FURTHER FORCE OR EFFECT, AND TENANT SHALL HAVE NO RIGHT OR OPTION TO VOID THIS AMENDMENT PURSUANT TO THIS PARAGRAPH 13 OR OTHERWISE AT ANY TIME AFTER THE CONTINGENCY DEADLINE. FURTHERMORE, TENANT SHALL HAVE THE RIGHT, EXERCISED BY WRITTEN NOTICE TO LANDLORD DELIVERED ANY TIME PRIOR TO THE CONTINGENCY DEADLINE (THE “CONTINGENCY SATISFACTION NOTICE”), TO WAIVE THE CONTINGENCY AND TENANT’S RIGHT TO VOID THIS AMENDMENT PURSUANT TO THE CONTINGENCY. THE CONTINGENCY SATISFACTION NOTICE SHALL BE IRREVOCABLE. AS A CONDITION PRECEDENT TO ANY TERMINATION OF THIS AMENDMENT PURSUANT TO THE PROVISIONS OF THIS PARAGRAPH 13, IN ADDITION TO TENANT’S DELIVERY OF ITS CONTINGENCY TERMINATION NOTICE, TENANT MUST HAVE DELIVERED TO LANDLORD WITH ITS CONTINGENCY TERMINATION NOTICE AN AMOUNT AS A REIMBURSEMENT TO LANDLORD (COLLECTIVELY, THE “CONTINGENCY FEE”) EQUAL TO THE SUM OF ALL ARCHITECTURAL FEES, PERMITTING FEES, AND ATTORNEYS’ FEES INCURRED BY LANDLORD IN CONNECTION WITH THIS AMENDMENT AND THE EXPANSION AND EXTENSION CONTEMPLATED HEREIN THROUGH THE DATE OF THE CONTINGENCY TERMINATION NOTICE. IF TENANT DULY AND TIMELY GIVES THE CONTINGENCY TERMINATION NOTICE AND PAYS THE CONTINGENCY FEE, THEN (A) THIS AMENDMENT SHALL TERMINATE, PROVIDED THAT THIS PARAGRAPH 13 SHALL SURVIVE SUCH TERMINATION, AND (B) THE LEASE SHALL CONTINUE IN FULL FORCE AND EFFECT, THE SAME AS THOUGH THIS AMENDMENT HAD NEVER BEEN ENTERED INTO (I.E., THE PREMISES SHALL REMAIN 14,462 RENTABLE SQUARE FEET AND THE TERM SHALL EXPIRE AT MIDNIGHT ON JANUARY 31, 2015,

SUBJECT TO AND IN ACCORDANCE WITH THE LEASE). OTHERWISE, THE LEASE, AS AMENDED HEREIN, SHALL CONTINUE IN FULL FORCE AND EFFECT IN ACCORDANCE WITH THE TERMS HEREOF. TENANT ACKNOWLEDGES AND AGREES THAT: (A) AS A RESULT OF THE CONTINGENCY, AND IN ORDER TO MINIMIZE THE CONTINGENCY FEE DUE HEREUNDER, LANDLORD SHALL NOT COMMENCE CONSTRUCTION OF THE IMPROVEMENTS UNTIL SUCH TIME AS THE CONTINGENCY HAS EXPIRED AND TENANT HAS NO FURTHER RIGHT TO TERMINATE OR VOID THIS AMENDMENT (PROVIDED, HOWEVER, THAT THE FOREGOING SHALL NOT PROHIBIT LANDLORD FROM PREPARING FOR CONSTRUCTION OF THE IMPROVEMENTS, INCLUDING BUT NOT LIMITED TO THE PREPARATION OF A SPACE PLAN AND CONSTRUCTION DOCUMENTS AND THE PULLING OF ANY APPLICABLE PERMITS, AND PROVIDED FURTHER THAT THE COSTS INCURRED BY LANDLORD IN CONNECTION WITH ANY SUCH PREPARATION SHALL BE INCLUDED IN THE CONTINGENCY FEE); AND (B) IN CONSIDERATION FOR TENANT’S RIGHT TO VOID THIS AMENDMENT PURSUANT TO THE CONTINGENCY, IF TENANT (1) DOES NOT DELIVER THE CONTINGENCY TERMINATION NOTICE AND THE CONTINGENCY FEE TO LANDLORD ON OR BEFORE THE CONTINGENCY DEADLINE, OR (2) DELIVERS THE CONTINGENCY SATISFACTION NOTICE TO LANDLORD PRIOR TO THE CONTINGENCY DEADLINE, TENANT SHALL COMMENCE PAYING RENT (INCLUDING, WITHOUT LIMITATION, BASE RENT AND TENANT’S SHARE OF INCREASES IN TAXES AND OPERATING EXPENSES) FOR THE PREMISES (AS EXPANDED BY THE EXPANSION SPACE) ON THE EFFECTIVE DATE, SUBJECT TO THE ABATEMENT, DESPITE THAT THE IMPROVEMENTS HAVE NOT YET BEEN CONSTRUCTED.

14.Brokers. Tenant represents and warrants to Landlord that neither it nor its officers or agents nor anyone acting on its behalf has dealt with any real estate broker other than LaVista Associates, Inc. which represented Landlord, and ICON Commercial Interests, L.L.C., which represented Tenant, in the negotiating and making of this Amendment, and Tenant agrees to indemnify and hold Landlord, its agents, employees, partners, directors, shareholders and independent contractors harmless from all liabilities, costs, demands, judgments, settlements, claims, and losses, including reasonable attorneys’ fees and costs, incurred by Landlord in conjunction with any such claim or claims of any other broker or brokers claiming to have interested Tenant in the Building, the Original Premises or the Expansion Space or claiming to have caused Tenant to enter into this Amendment.

15.Authority. The person signing this Amendment on behalf of Tenant hereby represents and warrants that (i) he/she is authorized to execute this Amendment on behalf of Tenant, (ii) he/she possesses the requisite power and authority to bind Tenant to the terms and provisions hereof, (iii) Tenant has taken all actions necessary to authorize the execution, delivery and performance of this Amendment by Tenant, and (iv) Tenant has been duly organized and is qualified or authorized to do business in the State in which the Premises are located. Furthermore, Tenant agrees to take any and all necessary action to keep its existence as an entity in good standing throughout the Term, as extended herein and as may be further extended, in the State in which Tenant has been organized as well as to remain qualified to do business within the State in which the Premises are located.

16.    No Defaults. Tenant hereby agrees that there are, as of the date hereof, regardless of the giving of notice or the passage of time, or both, no defaults or breaches on the part of Landlord or Tenant under the Lease.

17.Headings. The headings used herein are provided for convenience only and are not to be considered in construing this Amendment.

18.Entire Agreement. This Amendment represents the entire agreement between the parties with respect to the subject matter hereof. Landlord and Tenant agree that there are no collateral or oral agreements or understandings between them with respect to the Original Premises, the Expansion Space or the Building other than the Lease and this Amendment. This Amendment supersedes all prior negotiations, agreements, letters or other statements with respect to the matters addressed herein.

19.Binding Effect. This Amendment shall not be valid and binding on Landlord and Tenant unless and until it has been completely executed by and delivered to both parties.

20.Restatement; Confirmation of Lease. From and after the date of this Amendment, the Prior Seventh Amendment shall be null and void and of no further force or effect. From and after the date of this Amendment, Tenant’s occupancy of the Premises, as described and expanded herein, and the relationship of landlord and tenant between Landlord and Tenant, shall be governed by the provisions of the Lease, as amended by this Amendment, which Amendment shall completely supersede the Prior Seventh Amendment as of such date. All rights and obligations of Landlord and Tenant for periods prior to the date of this Amendment shall continue to be governed by the Lease. Except as expressly amended and modified by this Amendment, the Lease shall otherwise remain unmodified and in full force and effect, the parties hereto hereby ratifying and confirming the same. To the extent of any inconsistency between the Lease and this Amendment, the terms of this Amendment shall control.

IN WITNESS WHEREOF, the undersigned parties have duly executed this Amendment under seal as of the day and year first above written.

COMPANY (U.S.A.), a wholly owned subsidiary of

Manulife Financial Corporation

By: /s/ Richard J. Strom

Print Name: Richard J. Strom

Title: Managing Director, Southeast US

Real Estate Asset Management

ALIMERA SCIENCES, INC.,

a Delaware corporation

By: /s/ Dan Myers

Name: Dan Myers

Title: President/CEO