Master Terms & Conditions of Sale between Illumina, Inc. and the Registrant, dated May 28, 2019

Exhibit 10.3

Certain information has been excluded from this exhibit because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

Master Terms and Conditions of Sale

(Illumina Advantage Products)

These MASTER TERMS AND CONDITIONS OF SALE (these “Terms”) are entered into effective as of May 28, 2019 (the “Effective Date”) by and between Illumina, Inc., a Delaware corporation with a business address at 5200 Illumina Way, San Diego, California 92122 (together with its Affiliates, “Illumina”), and Adaptive Biotechnologies Corporation, a Washington corporation with a business address at 1551 Eastlake Avenue East, Suite 200, Seattle, Washington 98102 (together with its Affiliates, “Adaptive”). Illumina and Adaptive are collectively referred to as the “Parties”, and each individually as a “Party”. For purposes of these Terms, the term “Affiliate” means, with respect to a Party, any entity directly controlling, controlled by, or under common control with such Party, for only so long as that control exists. For purposes of this definition, “control” means (a) in the case of a corporate entity, direct ownership of at least fifty percent of the stock or shares having the right to vote (or whatever lesser percentage that is the maximum allowed to be owned by a foreign corporation in a particular jurisdiction) for the election of directors of the entity, or (b) in the case of an entity that is not a corporate entity, the possession of the power to direct, or cause the direction of, the management or policies of the entity, whether through the ownership of voting securities, by contract, or otherwise. The terms “controlling,” “controlled by”, and “under common control with” have meanings comparable to the foregoing definition of “control”.

For good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties hereby agree as follows:

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

Purchaser is solely responsible for determining whether Purchaser has all intellectual property rights that are necessary for Purchaser’s intended uses of the Product.

EXCEPT FOR INDEMNIFICATION OBLIGATIONS HEREUNDER, BREACHES OF CONFIDENTIALITY HEREUNDER, OR SUCH PARTY’S GROSS NEGLIGENCE OR WILLFUL MISCONDUCT, TO THE EXTENT PERMITTED BY LAW, SELLER’S TOTAL AND CUMULATIVE LIABILITY TO PURCHASER OR ANY THIRD PARTY ARISING OUT OF OR IN CONNECTION WITH THESE TERMS, INCLUDING WITHOUT LIMITATION, THE PRODUCT (INCLUDING USE THEREOF) AND SELLER’S PERFORMANCE, WHETHER IN CONTRACT, TORT (INCLUDING NEGLIGENCE), STRICT LIABILITY OR OTHERWISE, SHALL IN NO EVENT EXCEED THE AMOUNT PAID TO SELLER IN THE PARTICULAR ORDER THAT DIRECTLY CAUSED THE LIABILITY.

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

a. Warranty for Consumables. Seller warrants that Consumables will conform to their Specifications until the later of (i) for Advantage Consumables, [***] from the date of shipment from Seller, and for Temporary Consumables, [***] from the date of shipment from Seller, or (ii) any expiration date or the end of the shelf-life pre-printed on such Consumable by Seller, but in either event, no later than [***] from the date of shipment.

b. Exclusions from Warranty Coverage. The foregoing warranties do not apply to the extent a non-conformance is due to (i) abuse, misuse, neglect, negligence, accident, improper storage, or use contrary to the Documentation or Specifications, (ii) use that is an Excluded Use, (iii) improper handling, installation, maintenance, or repair (other than if performed by Seller’s personnel), (iv) unauthorized alterations, (v) force majeure events, or (vi) use with a third party’s good (unless the Product’s Documentation or Specifications expressly state such third party’s good is for use with the Product).

c. Procedure for Warranty Coverage. In order to be eligible for repair or replacement under this warranty Purchaser must (i) promptly contact Seller’s support department to report the non-conformance, (ii) cooperate with Seller in confirming or diagnosing the non-conformance, and (iii) return the Product, transportation charges prepaid to Seller following Seller’s instructions, or, if agreed by Seller and Purchaser, grant Seller’s authorized repair personnel access to the Product in order to confirm the non-conformance and make repairs.

d. Sole Remedy under Warranty. Seller will, at its option, repair or replace non-conforming Product that is covered by this warranty, provided that Seller can reasonably identify and confirm such nonconformance. Seller will use commercially reasonable efforts to provide replacement Advantage Consumables in Purchaser’s next scheduled shipment where single lot per shipment can be maintained. In the event replacement Consumables are included as a single lot with the next scheduled shipment, the warranty period for replacement Consumables is equal to that of the rest of the lot. In all other cases, the warranty period for repaired or replaced Consumables is [***] days from the date of shipment or the remaining period on the original Consumables warranty, whichever is later. In no event will the warranty for repaired or replaced Consumables be later than [***] from the date of shipment. The preceding states Purchaser’s sole remedy and Seller’s sole obligations under the warranty.

a. Indemnification by Seller. Subject to these Terms, including without limitation, the Exclusions to Seller Indemnification Obligations (Section 11(b) below) and the Conditions to Indemnification Obligations (Section 11(d) below), Seller shall (i) defend, indemnify, and hold harmless Purchaser against any third-party claim or action alleging that the Product when used for Clinical Use on samples from the Collection Territory, or for research use, in accordance with these Terms, in accordance with the Documentation or Specifications, where such third-party claim or action could be brought without regard to any specific fields of use or specific applications, infringes the valid and enforceable intellectual property rights of a third party, and (ii) pay all settlements entered into by, and all final judgments and costs (including reasonable attorneys’ fees) awarded against, Purchaser in connection with such infringement claim. If the Product or any part thereof, becomes, or in Seller’s opinion may become, the subject of an infringement claim, Seller shall have the right, at its option, to (A) procure for Purchaser the right to continue using the Product, (B) modify or replace the Product with a substantially equivalent non-infringing substitute, or (C) require the return of the Product and terminate the rights, license, and any other permissions provided to Purchaser with respect the Product and refund to Purchaser the depreciated value (as shown in Purchaser’s official

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

records) of the returned Product at the time of such return; provided that, no refund will be given for used-up or expired Consumables. This Section states the entire liability of Seller for any infringement of third party intellectual property rights.

b. Exclusions to Seller Indemnification Obligations. For the avoidance of doubt, Seller has no obligation to defend, indemnify, or hold harmless Purchaser for any infringement claim to the extent such infringement arises from: (i) use of the Product for any Excluded Use, (ii) use of the Product in any manner not in accordance with the rights expressly granted to Purchaser under these Terms, (iii) use of the Product in combination with any third party products, materials, or services (unless the Product’s Documentation or Specifications expressly state such third party’s good is for use with the Product), (iv) use of the Product to perform any assay or other process not supplied by Seller (v) Seller’s compliance with specifications or instructions for such Product furnished by, or on behalf of, Purchaser, (vi) Purchaser’s breach of any of these Terms, or (vii) use of stand-alone third party goods that may be acquired or used with the Products (each of (i) – (vii), is referred to as an “Excluded Claim”).

c. Indemnification by Purchaser. Purchaser shall defend, indemnify, and hold harmless Seller, its Affiliates, their non-affiliate collaborators and development partners that contributed to the development of the Product, and their respective officers, directors, representatives, and employees against any claims, liabilities, damages, fines, penalties, causes of action, and losses of any and every kind (including reasonable attorneys fees), including without limitation, personal injury or death claims, and infringement of a third party’s intellectual property rights, resulting from, relating to, or arising out of (i) any Excluded Claim, or (ii) Purchaser’s marketing, sale, and/or provision of services, including without limitation, harm from misdiagnosis, missed diagnoses, and actions or inactions taken as a result of information provided directly or indirectly by Purchaser to patients, physicians, or other entities. Notwithstanding the foregoing, nothing herein shall be deemed to require Purchaser to indemnify Seller, its Affiliates, their non-affiliate collaborators and development partners that contributed to the development of the Product for the negligence or willful misconduct of any such entites.

d. Conditions to Indemnification Obligations. The Parties’ indemnification obligations are conditioned upon the Party seeking indemnification (i) promptly notifying the other Party in writing of such claim or action, (ii) giving the other Party exclusive control and authority over the defense and settlement of such claim or action, (iii) not admitting infringement of any intellectual property right without prior written consent of the other Party, (iv) not entering into any settlement or compromise of any such claim or action without the other Party’s prior written consent, and (v) providing reasonable assistance to the other Party in the defense of the claim or action; provided that, the indemnifying Party reimburses the indemnified Party for its reasonable out-of-pocket expenses incurred in providing such assistance.

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

a. Definition. The term “Confidential Information” means the proprietary and confidential information disclosed by on behalf of one Party (the “Disclosing Party”) to the other Party (the “Receiving Party”) in connection with these Terms, except any portion of the information that (a) is known to the Receiving Party at the time of the disclosure, as evidenced by its written records or other competent evidence, (b) is disclosed to the Receiving Party by a third person who to the Receiving Party’s knowledge was lawfully in possession of such information and not under an obligation of nondisclosure, (c) is published or generally known to the public, either before or after the date of disclosure through no breach of this Section on the part of the Receiving Party, or (d) is developed by or for the Receiving Party without use or reliance upon the disclosing party’s Confidential Information as evidenced by the Receiving Party’s written records or other competent evidence. Confidential Information includes all information concerning the discussions and negotiations relating to, and the terms and existence of, these Terms.

b. Obligation. In the course of the performance of these Terms and orders hereunder, including potential discussions for orders and additional product to these Terms, the Disclosing Party may disclose Confidential Information to the Receiving Party. Except as permitted by these Terms, the Receiving Party shall not disclose Confidential Information received from the Disclosing Party to any third party, except to its Affiliates, employees, advisors, agents, and consultants (collectively, “Permitted Recipients”) who in the Receiving Party’s judgment, have a need to know such Confidential Information for the purpose of the Receiving Party’s performance of its obligations under these Terms or the enforcement of its rights under these Terms. The Receiving Party shall not, and shall ensure that its Permitted Recipients do not, use the Disclosing Party’s Confidential Information for any purpose except for the purpose of fulfilling the Receiving Party’s performance of its obligations under these Terms or the enforcement of its rights under these Terms. Notwithstanding the foregoing, nothing herein shall be construed as preventing the Receiving Party from disclosing any quotes, pricing terms, or other relevant portions of the Disclosing Party’s Confidential Information in confidence to third parties in connection with and necessary for the planning, negotiation, or implementation of any merger, acquisition, sale of a going concern, securities sale or transfer, financing transaction, corporate reorganization, or other M&A transaction, so long as such third parties are under an obligation of confidentiality and non-use at least as protective as those set forth in these Terms; provided that the Receiving Party shall be responsible for any unauthorized disclosures of such Confidential Information by such third parties.

c. Compelled Disclosure. If Confidential Information is required by law to be disclosed by the Receiving Party, to defend or prosecute litigation, or to comply with governmental regulations, Receiving Party may disclose the Confidential Information in connection thereto provided that the Receiving Party gives the Disclosing Party prompt prior written notice of such legal requirement, such that the Disclosing Party has the opportunity to apply for confidential treatment of such Confidential Information, and reasonably cooperates therewith.

d. Return or Destroy. Upon the end of the Term (as defined in Section 18 below), the Receiving Party shall, if so requested by the Disclosing Party, promptly return to the Disclosing Party or destroy the originals and all copies of any Confidential Information (including all extracts, summaries and derivatives thereof) then in the Receiving Party’s possession or under the Receiving Party’s control. Notwithstanding the foregoing, the Receiving Party may retain one copy of such Confidential Information for legal archival purposes and need not destroy automatic backups of their computer systems made in the ordinary course of business. All retained Confidential Information will remain subject to the terms of this Section 17.

e. Public Announcements. Neither Party shall make any public announcement concerning the transactions contemplated herein, or make any public statement that includes the name of the other Party or any of its Affiliates, or otherwise use the name of the other Party or any of its Affiliates in any public statement or public document without the prior written consent of the other Party, except and to the extent as may be required by law, regulation (including SEC regulation), or judicial order, in which case the Party required to make the public announcement or public statement shall use commercially reasonable efforts to obtain the approval of the other Party as to form, nature, and extent of the public announcement or public statement prior to issuing the same, unless reflective of prior public announcements previously agreed to regarding the general relationship between the parties.

f. Injunctive Relief. Each Party may suffer irreparable damage if its Confidential Information is used or disclosed to any third party in violation of this Section. In the event of any breach or threatened breach of this Section by the Receiving Party or any of its Permitted Recipients, the Disclosing Party may be entitled to equitable relief, including the granting of an injunction and specific performance, without proof of actual damages, in addition to all other remedies available to the Disclosing Party at law or in equity.

a. Applicability of Terms and Conditions. These Terms exclusively govern the ordering, purchase, supply, and use of Product, and override any conflicting, amending, and/or additional terms contained in any purchase orders, invoices, order confirmations, or similar documents, all of which are hereby rejected and are null and void. Acceptance of a purchase order occurs when Seller provides an order confirmation. Seller’s failure to object to any such terms shall not constitute a waiver by Seller, nor constitute acceptance by Seller of such terms and conditions. Third party products may be subject to additional terms and conditions.

b. Order Changes/Cancellations. Orders for Products may not be changed or cancelled once placed, except as required in Section 9. Seller reserves the right to charge Purchaser up to [***]% of the purchase price of the canceled order for such Advantage Consumables, and Purchaser agrees to make payment on any and all invoices provided by Seller for such charges.

c. Governing Law. These Terms, their interpretation, and the performance of the Parties shall be governed by the laws of the State of California, U.S.A., without giving effect to its choice of law principles. Seller and Purchaser agree that the United Nations Convention on Contracts for the International Sale of Goods shall not apply to these Terms, including any terms in the Documentation.

d. Dispute Resolution. The Parties will use reasonable efforts to settle all matters in dispute between them amicably. If a dispute or claim arises out of or is related to these Terms, or the breach, termination, or invalidity thereof, the Parties agree first to try in good faith to settle the dispute by escalation to senior management in their respective organizations before resorting to litigation. Any dispute or claim arising out of or in relation to Terms, or the breach, termination, or invalidity thereof, that cannot be so resolved shall be settled exclusively by a State or

Certain information, as identified by [***], has been excluded from this agreement because it (i) is not material and (ii) would be competitively harmful if publicly disclosed.

Federal court of competent jurisdiction located within San Diego County, California, U.S.A., including any appellate courts with jurisdiction over such courts, and each Party irrevocably submits to the exclusive jurisdiction and venue of any such court to resolve any such dispute or claim.

e. Representations and Warranties. Purchaser is not an authorized dealer, representative, reseller, or distributor of any of Seller’s, or Seller’s Affiliates’, products or services. Purchaser represents, and warrants that it (i) is not purchasing the Product on behalf of a third party, (ii) is not purchasing the Product in order to resell or distribute the Product to a third party, (iii) is not purchasing the Product in order to export the Product from the country in which Seller shipped the Product pursuant to the ship-to address designated by Purchaser at the time of ordering (“Ship-To Country”), and (iv) will not export the Product out of the Ship-To Country.

f. Remedies for Breach. In addition to any remedies specified elsewhere under these Terms, and any remedies available to a Party under law or in equity, in the event the other Party breaches these Terms, a Party may do any, all, or any combination of the following: (i) cease further shipments of Product, (ii) terminate the rights granted to Purchaser pursuant to Section 3 (Rights to Product Upon Purchase), (iii) terminate any remaining product warranty for the affected Product, (iv) require Purchaser to immediately pay any unpaid and undisputed invoices, or (v) place a final order to cover transition (which shall be fulfilled by Seller in accordance with these terms, to the extent supply is available for Purchaser), and terminate these Terms.

g. Future Products. Any future products and/or services (“Unreleased Products”) are subject to new part numbers, pricing, and specifications and the acquisition of Product hereunder is not in reliance on the availability of any Unreleased Products.

h. Seller Affiliates. Any actions or rights that may be performed or exercised by Seller may be performed or exercised by Seller itself or by any of its Affiliates. By way of non-limiting example, Seller’s Affiliates may carry out shipment, servicing, invoicing, and receipt of payment.

i. Force Majeure. Seller is not responsible for any failure to perform or delay attributable in whole or in part to any cause beyond its reasonable control, including but not limited to acts of God, fire, flood, tornado, earthquake, hurricane, lightning, government actions, actual or threatened acts of war, terrorism, civil disturbance or insurrection, sabotage, labor shortages or disputes, failure or delay in delivery by Seller’s suppliers or subcontractors, transportation difficulties, shortage of energy, raw materials or equipment, or Purchaser’s fault or negligence.

j. Notices. Any notice required or permitted shall be in writing and shall be deemed received (i) when delivered personally; (ii) five days after having been sent by registered or certified mail, return receipt requested, postage prepaid (or 10 days for international mail); or (iii) one day after deposit with a commercial express courier that provides written verification of receipt.

k. Seller Information. Seller may maintain and use a database of orders and account information pertaining to Purchaser for purposes of order processing, maintaining records, assisting with future orders of Purchaser, and compliance with applicable laws and regulations. Purchaser grants to Seller a non-exclusive, fully paid-up, royalty-free, worldwide, irrevocable, perpetual right and license, with the right to sublicense, to use and commercialize in any manner suggestions, ideas, or comments provided by Purchaser to Seller related to the manufacture, use or sale of the Products.

l. Export Compliance. The Products, any related technology, or information provided to Purchaser may be subject to restrictions and controls imposed by applicable laws, the United States Export Administration Act and the regulations thereunder (or the export regulations and laws of another country). Notwithstanding anything to the contrary in these Terms, Purchaser agrees not to use the Products in, or export or re-export the Products, any related technology, or information provided to Purchaser into, any country or to any person or entity, or in any manner, in violation of such controls or any other laws, rules, or regulations of any country, state, or jurisdiction.

m. Healthcare Law Compliance. Purchaser acknowledges and agrees that as a healthcare company, Seller, and Seller’s Affiliates, may be required by applicable law and regulation (“Healthcare Laws”) to disclose the existence of these Terms, the terms of herein including financial terms, and the subject matter. Seller agrees it, and its Affiliates, will disclose, as determined in its reasonable discretion, the least amount of information as possible in order to comply with such Healthcare Laws.

n. Assignment. Neither Party may assign these Terms or any part of these Terms without the prior written consent of the other Party; provided, however: (a) either Party may assign these Terms to one of its Affiliates that is not a direct competitor of the other Party without such consent; and (b) either Party, without such consent, may assign these Terms in connection with the transfer, sale, or divestiture of substantially all of its business to which these Terms pertains or in the event of its merger or consolidation with another company that is not a direct competitor of the other Party. Any permitted assignee shall assume all obligations of its assignor under this Agreement. No assignment shall relieve any Party of its responsibility hereunder.

o. Miscellaneous. Except as expressly stated in these Terms, no right or license under any of Seller, or Seller’s affiliates, intellectual property rights is or are granted expressly, by implication, or by estoppel. All references to days mean calendar days unless specifically stated otherwise. Seller may cease performance (including cancellation of any order outstanding) immediately without liability to Purchaser if Purchaser becomes the subject of a voluntary or involuntary petition in bankruptcy or any proceeding relating to insolvency, receivership, liquidation, or composition for the benefit of creditors. These Terms represent the entire agreement between the Parties regarding the subject matter hereof and supersede all prior discussions, communications, agreements, and understandings of any kind between the Parties. No amendment to these terms or waiver of any right, condition, or breach will be effective unless made in a writing signed by both Parties. If any provision is held invalid or unenforceable, such provision shall be enforced to the maximum extent permissible so as to give effect to the intent of the Parties, and the remaining terms will continue in full force and effect. The failure of either Party to exercise any right granted herein or to require any performance of any term or the waiver by either Party of any breach shall not prevent a subsequent exercise or enforcement of, or be deemed a waiver of any subsequent breach of, the same or any other term. Nothing herein shall constitute or create a joint venture, partnership, or any other similar arrangement between the Parties. There are no third party beneficiaries to these Terms.

p. Counterparts; Transmission. These Terms may be executed and transmitted by DocuSign or via email in Portable Document Format (PDF), and in any number of counterparts, each of which will be deemed to be an original, and all of which taken together will constitute one agreement binding on both Parties.

IN WITNESS WHEREOF, the Parties have caused the execution of these Terms by their respective authorized representatives, effective as of the Effective Date.