Amendment No. 1 to the License Agreement, dated February 1, 2017, between Epinomics and The Board of Trustees of the Leland Stanford Junior University

Exhibit 10.8

Amendment No. 1 to the

License Agreement Effective October 15^th, 2015

between Stanford University

And

Epinomics Inc.

Effective as of February 1^st, 2017, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (“Stanford”), an institution of higher education having powers under the laws of the State of California, and EPINOMICS (“Epinomics”), a company having a primary place of business at 1165A O’Brien Dr, Menlo Park, California 94025, agree as follows:

1.        Stanford and Epinomics are parties to a License Agreement effective October 15^th, 2015 (“Original Agreement”) covering “ATAC-seq: Fast and efficient chromatin hypersensitivity mapping in small cell numbers using direct transposition” disclosed in Stanford Docket S12-404.

Now, Epinomics has requested and Stanford has agreed to amend the Original Agreement to add an invention entitled “ATAC-see: a method for integrated imaging and sequencing of the accessible genome” disclosed in Stanford Docket S16-007.

“2.9 “Licensed Patent” means Stanford’s PCT application Serial Number PCT/US2014/38825 filed May 20, 2014. US patent application Serial Number 62/306,504 filed March 10^th, 2016, any foreign patent application corresponding thereto, and any divisional. continuation. or reexamination application, extension, and each patent that issues or reissues from any of these applications.”

IN WITNESS WHEREOF. the parties hereto have executed this Amendment No. 1 in duplicate originals by their duly authorized officers or representatives.