ZAFGEN, INC. Change of Control Agreements

First Amendment to Severance and Change-in-Control Agreement by and between Registrant and Priya Singhal dated September 12, 2019 (Filed With SEC on March 5, 2020)

First Amendment to Severance and Change-in-Control Agreement for Brian McVeigh dated September 12, 2019 (Filed With SEC on September 12, 2019)

First Amendment to Severance and Change-in-Control Agreement for Patricia Allen dated September 12, 2019 (Filed With SEC on September 12, 2019)

First Amendment to Severance and Change-in-Control Agreement for Jeffrey Hatfield dated September 12, 2019 (Filed With SEC on September 12, 2019)

Severance and Change in Control Agreement by and between the Registrant and Priya Singhal, M.D., M.P.H., effective as of March 4, 2019 (Filed With SEC on May 9, 2019)

Severance and Change in Control Agreement by and between Zafgen, Inc. and Brian P. McVeigh, effective as of May 29, 2018 (Filed With SEC on May 30, 2018)

Severance and Change in Control Agreement by and between Zafgen, Inc. and Jeffrey S. Hatfield, effective as of October 9, 2017 (Filed With SEC on October 12, 2017)

SEVERANCE AND CHANGE IN CONTROL AGREEMENT (Filed With SEC on August 5, 2016)