Amgen Inc. Bonus & Incentive Agreements

Form of Grant of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan (Filed With SEC on February 9, 2023)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan (Filed With SEC on February 9, 2023)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program (Filed With SEC on February 9, 2023)

Amgen Inc. Executive Incentive Plan (Filed With SEC on April 28, 2022)

Form of Grant of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended (Filed With SEC on February 16, 2022)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended (Filed With SEC on February 16, 2022)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended (Filed With SEC on February 16, 2022)

Form of Grant of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 1 (Filed With SEC on February 9, 2021)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December (Filed With SEC on February 9, 2021)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended on December 1 (Filed With SEC on February 9, 2021)

Amgen Inc. 2009 Director Equity Incentive Program. (As Amended (Filed With SEC on February 9, 2021)

Form of Grant of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 10, 2019.) (Filed With SEC on February 12, 2020)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 10, 2019.) (Filed With SEC on February 12, 2020)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended on December 10, 2019.) (Filed With SEC on February 12, 2020)

Amgen Inc. 2009 Director Equity Incentive Program. (As Amended on December 11, 2019.) (Filed With SEC on February 12, 2020)

Form of Restricted Stock Unit Agreement for the Amgen Inc. 2009 Director Equity Incentive Program. (As Amended on December 11, 2019.) (Filed With SEC on February 12, 2020)

Form of Cash-Settled Restricted Stock Unit Agreement for the Amgen 2009 Director Equity Incentive Program. (As Amended on December 11, 2019.) (Filed With SEC on February 12, 2020)

Form of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 7, 2018.) (Filed With SEC on February 13, 2019)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 7, 2018.) (Filed With SEC on February 13, 2019)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended on December 7, 2018.) (Filed With SEC on February 13, 2019)

Form of Stock Option Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 12, 2017.) (Filed With SEC on February 13, 2018)

Form of Restricted Stock Unit Agreement for the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan. (As Amended on December 12, 2017.) (Filed With SEC on February 13, 2018)

Amgen Inc. 2009 Performance Award Program. (As Amended on December 12, 2017.) (Filed With SEC on February 13, 2018)

Form of Performance Unit Agreement for the Amgen Inc. 2009 Performance Award Program. (As Amended on December 12, 2017.) (Filed With SEC on February 13, 2018)

Amgen Inc. 2009 Director Equity Incentive Program. (As Amended on October 24, 2017.) (Filed With SEC on February 13, 2018)

Form of Restricted Stock Unit Agreement for the Amgen Inc. 2009 Director Equity Incentive Program. (As Amended on October 24, 2017.) (Filed With SEC on February 13, 2018)

Form of Cash-Settled Restricted Stock Unit Agreement for the Amgen 2009 Director Equity Incentive Program (Filed With SEC on February 13, 2018)

Second Amendment to the Amgen Inc. Executive Incentive Plan, effective January 1, 2017 (Filed With SEC on April 27, 2017)

Second Amendment to the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan, As Amended (Filed With SEC on May 2, 2016)

AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM (Effective March 3, 2009) As Amended Through March 2, 2016 ARTICLE I PURPOSE (Filed With SEC on May 2, 2016)

First Amendment to the Amgen Inc. Amended and Restated 2009 Equity Incentive Plan (Filed With SEC on April 27, 2015)

AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM (Effective March 3, 2009) As Amended Through December 13, 2013 ARTICLE I PURPOSE (Filed With SEC on February 24, 2014)

AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM (Effective March 3, 2009) As Amended Through March 6, 2013 ARTICLE I PURPOSE (Filed With SEC on May 3, 2013)

AMGEN INC. 2009 DIRECTOR EQUITY INCENTIVE PROGRAM (Effective January 1, 2013) As Amended and Restated December 13, 2012 and Subsequently Amended March 6, 2013 ARTICLE I PURPOSE (Filed With SEC on May 3, 2013)

RESTRICTED STOCK UNIT AGREEMENT (Director Equity Incentive Program) (Filed With SEC on May 3, 2013)

AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM (Effective March 3, 2009) As Amended December 13, 2012 ARTICLE I PURPOSE (Filed With SEC on February 27, 2013)

AMGEN INC. 2009 DIRECTOR EQUITY INCENTIVE PROGRAM (Effective January 1, 2013) As Amended and Restated December 13, 2012 ARTICLE I PURPOSE (Filed With SEC on February 27, 2013)

RESTRICTED STOCK UNIT AGREEMENT (Director Equity Incentive Program) (Filed With SEC on February 27, 2013)

FIRST AMENDMENT TO THE AMGEN INC. EXECUTIVE INCENTIVE PLAN (AMENDED AND RESTATED EFFECTIVE JANUARY 1, 2009) (Filed With SEC on February 27, 2013)

AMGEN INC. 2009 PERFORMANCE AWARD PROGRAM (Effective March 3, 2009) As Amended March 14, 2012 ARTICLE I PURPOSE (Filed With SEC on May 8, 2012)