ALNYLAM PHARMACEUTICALS, INC. Bonus & Incentive Agreements

Form of Performance Stock Unit Award Agreement for Executive Officers under 2018 Stock Incentive Plan, as amended (Filed With SEC on May 4, 2023)

Form of Restricted Stock Unit Award Agreement for Executive Officers under 2018 Stock Incentive Plan, as amended (Filed With SEC on May 4, 2023)

Amended and Restated 2018 Stock Incentive Plan (Filed With SEC on July 28, 2022)

Forms of Nonstatutory Stock Option Agreements under 2018 Stock Incentive Plan, as amended (Filed With SEC on February 10, 2022)

Forms of Stock Unit Award Agreements under 2018 Stock Incentive Plan, as amended (Filed With SEC on February 10, 2022)

Amended and Restated Annual Incentive Program, as amended (Filed With SEC on February 11, 2021)

Amended and Restated Annual Incentive Program (Filed With SEC on February 13, 2020)

2018 Stock Incentive Plan, as amended (Filed With SEC on August 6, 2019)

Form of Ex-US Restricted/Performance Stock Unit Award Agreement under 2018 Stock Incentive Plan, as amended (Filed With SEC on August 6, 2019)

2018 Stock Incentive Plan (Filed With SEC on August 2, 2018)

Forms of Incentive Stock Option Agreement, Nonstatutory Stock Option Agreements, Restricted Stock Agreement and Restricted Stock Unit Award Agreement under 2018 Stock Incentive... (Filed With SEC on August 2, 2018)

ALNYLAM PHARMACEUTICALS, INC. SECOND AMENDED AND RESTATED 2009 STOCK INCENTIVE PLAN (Filed With SEC on August 9, 2017)

ALNYLAM PHARMACEUTICALS, INC. Incentive Stock Option Agreement Granted Under Second Amended and Restated 2009 Stock Incentive Plan (Filed With SEC on August 9, 2017)

Alnylam Pharmaceuticals, Inc. 2016 Annual Incentive Program (Filed With SEC on May 4, 2016)

ALNYLAM PHARMACEUTICALS, INC. AMENDED AND RESTATED 2009 STOCK INCENTIVE PLAN (including amendment through March 2, 2016) (Filed With SEC on May 4, 2016)

ALNYLAM PHARMACEUTICALS, INC. AMENDED AND RESTATED 2009 STOCK INCENTIVE PLAN (Filed With SEC on August 7, 2015)

ALNYLAM PHARMACEUTICALS, INC. Incentive Stock Option Agreement Granted Under Amended and Restated 2009 Stock Incentive Plan (Filed With SEC on August 7, 2015)

ALNYLAM PHARMACEUTICALS, INC. Nonstatutory Stock Option Agreement Granted Under Amended and Restated 2009 Stock Incentive Plan (Filed With SEC on August 7, 2015)

Alnylam Pharmaceuticals, Inc. 2015 Annual Incentive Program (Filed With SEC on May 8, 2015)

ALNYLAM PHARMACEUTICALS, INC. AMENDED AND RESTATED 2004 STOCK INCENTIVE PLAN (Filed With SEC on August 8, 2014)

ALNYLAM PHARMACEUTICALS, INC. Incentive Stock Option Agreement Granted Under Amended and Restated 2004 Stock Incentive Plan (Filed With SEC on August 8, 2014)

ALNYLAM PHARMACEUTICALS, INC. 2009 STOCK INCENTIVE PLAN, AS AMENDED (Filed With SEC on August 8, 2014)

ALNYLAM PHARMACEUTICALS, INC. Incentive Stock Option Agreement Granted Under 2009 Stock Incentive Plan (Filed With SEC on August 8, 2014)

ALNYLAM PHARMACEUTICALS, INC. Nonstatutory Stock Option Agreement Granted Under 2009 Stock Incentive Plan (Filed With SEC on August 8, 2014)

Alnylam Pharmaceuticals, Inc. 2014 Annual Incentive Program (Filed With SEC on May 9, 2014)

ALNYLAM PHARMACEUTICALS, INC. 2009 STOCK INCENTIVE PLAN, AS AMENDED (Filed With SEC on August 9, 2013)

Alnylam Pharmaceuticals, Inc. 2013 Annual Incentive Program (Filed With SEC on May 7, 2013)

Alnylam Pharmaceuticals, Inc. 2012 Annual Incentive Program (Filed With SEC on May 3, 2012)

EX-10.9 Forms of Incentive Stock Option Agreement and Nonstatutory Stock Option Agreement (Filed With SEC on February 26, 2010)

EX-10.16 2010 Annual Incentive Program (Filed With SEC on February 26, 2010)

Ex-10.1 Amended and Restated 2004 Stock Incentive Plan (Filed With SEC on August 7, 2009)

Ex-10.2 2009 Stock Incentive Plan (Filed With SEC on August 7, 2009)

Ex-10.1 2009 Annual Incentive Program (Filed With SEC on May 8, 2009)

EX-10.3 2004 Stock Incentive Plan, as amended (Filed With SEC on March 10, 2008)

EX-10.3 Forms of Incentive Stock Option (Filed With SEC on August 11, 2005)

EX-10.2 2004 STOCK INCENTIVE PLAN (Filed With SEC on June 10, 2005)

EX-10.3 2004 STOCK INCENTIVE PLAN (Filed With SEC on May 10, 2004)

Ex-10.3 2004 Stock Incentive Plan (Filed With SEC on April 29, 2004)

EX-10.3 2004 STOCK INCENTIVE PLAN (Filed With SEC on April 6, 2004)