NAVIDEA BIOPHARMACEUTICALS, INC. Stock Agreements

Stock Purchase Agreement dated as of May 22, 2023 between Navidea Biopharmaceuticals, Inc. and Donald E. Garlikov (Filed With SEC on May 25, 2023)

Stock Purchase Agreement dated as of May 22, 2023 between Navidea Biopharmaceuticals, Inc. and Irwin Bain (Filed With SEC on May 25, 2023)

Common Stock Purchase Agreement dated as of April 26, 2023 between Navidea Biopharmaceuticals, Inc. and Keystone Capital Partners, LLC (Filed With SEC on April 28, 2023)

First Amendment to Section 382 Rights Agreement dated as of January 10, 2023 between Navidea Biopharmaceuticals, Inc. and Continental Stock Transfer & Trust Company, LLC (Filed With SEC on January 10, 2023)

Certificate of Designations, Preferences and Rights of Series I Convertible Preferred Stock (Filed With SEC on August 2, 2022)

Certificate of Designations, Preferences and Rights of Series I Convertible Preferred Stock (Filed With SEC on July 20, 2022)

Section 382 Rights Agreement, dated as of April 7, 2022, between Navidea Biopharmaceuticals, Inc. and Continental Stock Transfer & Trust Company, LLC, as Rights Agent (Filed With SEC on April 12, 2022)

Amendment to Stock Purchase Agreement and Letter of Investment Intent by and between the Company and Investor dated July 8, 2021 (Filed With SEC on July 13, 2021)

Stock Purchase Agreement and Letter of Investment Intent by and between the Company and Investor dated March 2, 2021 (Filed With SEC on March 4, 2021)

Stock Purchase Agreement and Letter of Investment Intent, by and between the Company and Keystone (Filed With SEC on September 2, 2020)

Form of Common Stock Purchase Agreement (Filed With SEC on September 2, 2020)

Stock Purchase Agreement, effective August 9, 2020, by and between Navidea Biopharmaceuticals, Inc. and Jubilant Radiopharma (Filed With SEC on August 12, 2020)

Stock Purchase Agreement and Letter of Investment Intent by and between the Company and the Investor (Filed With SEC on May 12, 2020)

Stock Purchase Agreement, effective February 14, 2020, by and between Navidea Biopharmaceuticals, Inc. and Keystone Capital Partners, LLC (Filed With SEC on March 18, 2020)

Stock Purchase Agreement, effective February 14, 2020, by and between Navidea Biopharmaceuticals, Inc. and John K. Scott (Filed With SEC on March 18, 2020)

Stock Purchase Agreement, dated December 6, 2019, among Navidea Biopharmaceuticals, Inc. and the purchasers named therein (Filed With SEC on December 11, 2019)

Stock Purchase Agreement, dated March 22, 2019, between Navidea Biopharmaceuticals, Inc. and John K. Scott, Jr (Filed With SEC on May 9, 2019)

Stock Purchase Agreement dated September 13, 2018, by and between Navidea Biopharmaceuticals, Inc. and John K. Scott, Jr (Filed With SEC on November 9, 2018)

NEOPROBECORPORATION CERTIFICATEOF DESIGNATIONS, VOTING POWERS, PREFERENCES,LIMITATIONS, RESTRICTIONS, AND RELATIVE RIGHTSOF SERIES B CONVERTIBLE PREFERRED STOCK (Filed With SEC on June 28, 2010)

NEOPROBECORPORATION CERTIFICATEOF DESIGNATIONS, VOTING POWERS, PREFERENCES,LIMITATIONS, RESTRICTIONS, AND RELATIVE RIGHTSOF SERIES C CONVERTIBLE PREFERRED STOCK (Filed With SEC on June 28, 2010)

NEOPROBECORPORATION SECONDAMENDED AND RESTATED CERTIFICATE OF DESIGNATIONS, VOTINGPOWERS, PREFERENCES, LIMITATIONS, RESTRICTIONS,AND RELATIVE RIGHTS OF SERIES A 8%... (Filed With SEC on July 29, 2009)

SERIES AAWARRANT TO PURCHASE SHARES OFCOMMON STOCK OF NEOPROBECORPORATION ExpiresJuly 24, 2014 (Filed With SEC on July 29, 2009)

Exhibit4.1 NEOPROBECORPORATION FIRSTAMENDED AND RESTATED CERTIFICATE OF DESIGNATIONS, VOTINGPOWERS, PREFERENCES, LIMITATIONS, RESTRICTIONS,AND RELATIVE RIGHTS OF SERIES A 8%... (Filed With SEC on May 6, 2009)

FIRST AMENDMENT TO COMMON STOCK PURCHASE AGREEMENT (Filed With SEC on December 31, 2008)

COMMON STOCK PURCHASE AGREEMENT (Filed With SEC on December 4, 2006)