Biotechnology Industry Facility Agreements

Facility Agreement among the Company and Hanmi Pharmaceutical Co., Ltd dated August 27, 2024 (Aptose Biosciences Inc., Filed With SEC on November 12, 2024)

Working Capital Facility Agreement, dated August 9, 2023, by and among the Company, the several banks and other financial institutions or entities from time to time party thereto,... (HERON THERAPEUTICS, INC., Filed With SEC on August 14, 2023)

Facility Agreement, dated as of July 28, 2023, by and between the Registrant and China Merchants Bank Co., Ltd (BeiGene, Ltd., Filed With SEC on August 2, 2023)

Third Amendment to that certain Secured Convertible Facility Agreement, dated March 30, 2020, by and between AgeX Therapeutics, Inc. and Juvenescence Limited (AgeX Therapeutics, Inc., Filed With SEC on March 15, 2023)

Letter Agreement to Amend Term Debt Facility, dated March 9, 2022, between the Company and Mayne Pharma (HedgePath Pharmaceuticals, Inc., Filed With SEC on March 30, 2022)

Letter Agreement to Amend Term Debt Facility, dated January 13, 2022, between the Company and Mayne Pharma (HedgePath Pharmaceuticals, Inc., Filed With SEC on January 18, 2022)

Letter Agreement for Term Debt Facility, dated December 12, 2020, between the Company and Mayne Pharma (HedgePath Pharmaceuticals, Inc., Filed With SEC on December 17, 2020)

Second Amendment to Secured Convertible Facility Agreement, dated November 12, 2020, between AgeX Therapeutics, Inc. and Juvenescence Limited (AgeX Therapeutics, Inc., Filed With SEC on November 16, 2020)

First Amendment to Secured Convertible Facility Agreement, dated July 21, 2020, between AgeX Therapeutics, Inc. and Juvenescence Limited (AgeX Therapeutics, Inc., Filed With SEC on August 14, 2020)

Amendment to Senior Term Facilities Agreement by and between the registrant and MidCap Financial (Ireland) Limited, as agent, dated April 7, 2020 (Orchard Therapeutics plc, Filed With SEC on May 7, 2020)

Secured Convertible Facility Agreement, dated March 30, 2020, by and among AgeX Therapeutics, Inc., ReCyte Therapeutics, Inc., Reverse Bioengineering, Inc., and Juvenescence... (AgeX Therapeutics, Inc., Filed With SEC on March 30, 2020)

Amended and Restated Interim Facility Agreement, dated as of March 18, 2020, by and among Curetis GmbH, as Borrower, Crystal GmbH, a wholly owned subsidiary of the Registrant, as... (OPGEN INC, Filed With SEC on March 24, 2020)

Interim Facility Agreement, dated as of November 12, 2019, by and between Curetis GmbH, as Borrower and Crystal GmbH, a wholly owned subsidiary of the Registrant, as Lender (OPGEN INC, Filed With SEC on November 12, 2019)

Facility Improvement and Process Validation Agreement (Cellular Biomedicine Group, Inc., Filed With SEC on August 29, 2019)

Amendment No. 1 to the Facility Use Agreement, dated April 17, 2019, by and between Institute for Systems Biology and Neoleukin Therapeutics, Inc (AQUINOX PHARMACEUTICALS, INC, Filed With SEC on August 12, 2019)

Facility Use Agreement, dated December 4, 2018, by and between Institute for Systems Biology and Neoleukin Therapeutics, Inc (AQUINOX PHARMACEUTICALS, INC, Filed With SEC on August 12, 2019)

Second Amendment dated July 22, 2015 to Facility Agreement dated February 13, 2013 by and between the Company and Deerfield (WINDTREE THERAPEUTICS INC, Filed With SEC on July 24, 2015)

Amendment dated July 9, 2015 to Facility Agreement dated February 13, 2013 by and between the Company and Deerfield (WINDTREE THERAPEUTICS INC, Filed With SEC on July 9, 2015)

SECOND AMENDMENT TO FACILITY AGREEMENT (MANNKIND CORP, Filed With SEC on November 10, 2014)

FIRST AMENDMENT TO FACILITY AGREEMENT (INFINITY PHARMACEUTICALS, INC., Filed With SEC on November 10, 2014)

FACILITY AGREEMENT (Nuo Therapeutics, Inc., Filed With SEC on March 31, 2014)

Facility Agreement, dated February 13, 2013, between Discovery Laboratories, Inc. and Deerfield Private Design Fund II, L.P., Deerfield Private Design International II, L.P.,... (WINDTREE THERAPEUTICS INC, Filed With SEC on March 15, 2013)

FACILITY AGREEMENT (ARENA PHARMACEUTICALS INC, Filed With SEC on June 23, 2009)

FACILITY AGREEMENT (Exelixis, Filed With SEC on October 16, 2008)

FACILITY AGREEMENT (Exelixis, Filed With SEC on June 9, 2008)

Facility Reservation Agreement (NOVAVAX INC, Filed With SEC on March 15, 2002)

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Facility Agreements in the Biotechnology Industry