AVADEL PHARMACEUTICALS PLC Business Finance Contracts & Agreements

Indenture, dated as of April 3, 2023, by and between the Issuer, the Company and The Bank of New York Mellon, as Trustee (Filed With SEC on April 5, 2023)

Underwriting Agreement, dated March 29, 2023, by and between the Company and Jefferies LLC (Filed With SEC on March 30, 2023)

Purchase and Sale Agreement, dated March 29, 2023, between Avadel CNS Pharmaceuticals, LLC, the Company, Flamel Ireland Ltd., and RTW Royalty II DAC (Filed With SEC on March 30, 2023)

Form of Exchange Agreement between the Issuer, the Company and certain holders of the 2023 Notes (Filed With SEC on March 29, 2023)

Indenture, dated as of April 4, 2022, by and between the Issuer, the Company and The Bank of New York Mellon, as Trustee (Filed With SEC on April 5, 2022)

Form of Exchange Agreement between Avadel Finance Cayman Limited, Avadel Pharmaceuticals plc and certain holders of its February 2023 Notes (Filed With SEC on March 16, 2022)

Form of Exchange Agreement between the Issuer, the Company and certain holders of the Existing Notes (Filed With SEC on March 16, 2022)

Asset Purchase Agreement, dated as of June 30, 2020, by and between Avadel Seller, Seller Parent, Exela Buyer and Buyer Parent (Filed With SEC on July 2, 2020)

Underwriting Agreement, dated April 28, 2020, by and among the Company and Jefferies LLC, Piper Sandler & Co. and Stifel, Nicolaus & Company, Incorporated (Filed With SEC on April 29, 2020)

Registration Rights Agreement, dated February 25, 2020, by and among Avadel Pharmaceuticals plc and the Investors named therein (Filed With SEC on March 16, 2020)

Form of Registration Rights Agreement (Filed With SEC on February 24, 2020)

Securities Purchase Agreement, dated February 20, 2020, by and among Avadel Pharmaceuticals plc and the Investors named therein (Filed With SEC on February 24, 2020)

Binding Term Sheet between Avadel US Holdings, Inc. and Avadel Specialty Pharmaceuticals LLC (Filed With SEC on February 14, 2019)

First Supplemental Indenture, dated as of February 6, 2019, by and among Avadel Finance Cayman Limited, Avadel Pharmaceuticals plc, and The Bank of New York Mellon (Filed With SEC on February 7, 2019)

Asset Purchase Agreement by and among Cerecor, Inc. and Avadel Pharmaceuticals (USA), Inc., Avadel Pediatrics, Inc., FSC Therapeutics, LLC, Avadel US Holdings, Inc. and Avadel... (Filed With SEC on March 16, 2018)

Guarantee by Avadel US Holdings, Inc. and Avadel Pharmaceuticals plc in favor of Deerfield CSF, LLC, Peter Steelman and James Flynn dated as of February 16, 2018 (Filed With SEC on March 16, 2018)

Guarantee by Armistice Capital Master Fund, Ltd. in favor of Avadel US Holdings, Inc. dated as of February 16, 2018 (Filed With SEC on March 16, 2018)

Indenture, dated as of February 16, 2018, by and between the Issuer, the Company and The Bank of New York Mellon, as Trustee (Filed With SEC on February 16, 2018)

Form of U.S. Restricted Stock Unit Award Grant Notice and Agreement (Filed With SEC on December 8, 2017)

Renaissance Agreements Assignment and Assumption Agreement by and between Avadel Specialty Pharmaceuticals, LLC and Serenity Pharmaceuticals, LLC dated as of September 1, 2017 (Filed With SEC on November 9, 2017)

Form of Stock Option Agreement (Filed With SEC on June 30, 2017)

GUARANTY (Filed With SEC on March 28, 2017)

CONFIDENTIAL TREATMENT REQUESTED THEPORTIONS OF THIS AGREEMENT MARKED WITH ASTERISKS WITHIN BRACKETS (“[***]”) HAVE BEEN OMITTED PURSUANT TO A REQUESTFOR CONFIDENTIAL... (Filed With SEC on March 15, 2016)

FLAMELTECHNOLOGIES SociétéAnonyme au capital de 4 901 727 euros SiègeSocial : ParcClub du Moulin à Vent 33,avenue du Docteur Georges Lévy 69200VENISSIEUX R.C.S.LYON... (Filed With SEC on March 15, 2016)

MEMBERSHIP INTEREST PURCHASE AGREEMENT by and among FSC HOLDING COMPANY, LLC, a Delaware limited liability company, FSC THERAPEUTICS, LLC, a Delaware limited liability company,... (Filed With SEC on March 15, 2016)

FLAMELTECHNOLOGIES SOCIETE ANONYME AU CAPITAL DE 4 636 011 EUROS SiegeSocial : ParcClub du Moulin A Vent 33,avenue du Docteur Georges Lévy 69200VENISSIEUX R.C.S.LYON 379.001.530... (Filed With SEC on March 15, 2016)

FLAMELTECHNOLOGIES SOCIETE ANONYME AU CAPITAL DE 4 636 011 EUROS SiègeSocial : ParcClub du Moulin A Vent 33,avenue du Docteur Georges Lévy 69200VENISSIEUX R.C.S.LYON 379.001.530... (Filed With SEC on March 15, 2016)

FLAMELTECHNOLOGIES SOCIETE ANONYME WITH A STATED CAPITAL OF 5,029,783 EUROS RegisteredOffice: ParcClub du Moulin A Vent 33,avenue du Docteur Georges Lévy 69200VENISSIEUX... (Filed With SEC on March 15, 2016)